Immediate drug hypersensitivity reactions (IDHRs) are a burden for patients and the health
systems. This problem increases when taking into account that only a small proportion of …

Antibiotics are one of the most frequently prescribed drugs. Unfortunately, they also are the
most common cause for self-reported drug allergy, limiting the use of effective therapies …

Inflammation and immune responses are intricately intertwined processes crucial for
maintaining homeostasis and combating against pathogens. These processes involve …

Abstract Diagnosing Drug Hypersensitivity Reactions (DHRs) could be a complicated
process especially in children, since allergic‐like manifestation at this age is more often the …

Drug hypersensitivity reactions (DHRs) are a type of adverse drug reaction that can occur
with different classes of drugs and affect multiple organ systems and patient populations …

β-Lactamase inhibitors such as clavulanic acid and tazobactam were developed to
overcome β-lactam antibiotic resistance. Hypersensitivity reactions to these drugs have not …

Background Amoxicillin (AX) and clavulanic acid (CLV) are the betalactam antibiotics (BLs)
most used to treat bacterial infections, although they can trigger immediate hypersensitivity …

Immediate drug hypersensitivity reactions (IDHRs) are a burden for patients and the health
systems. This problem increases when taking into account that only a small proportion of …

Drug and chemical allergies are a significant public health concern, affecting millions of
people worldwide. They are often unpredictable, have a significant impact on the patients' …

Adverse Drug Reactions (ADRs) were defined in 1972 by the World Health Organisation
(WHO) as “a noxious and unintended effect occurring at doses normally used in man”. 2 …