Bone has a remarkable endogenous regenerative capacity that enables scarless healing
and restoration of its prior mechanical function, even under challenging conditions such as …

The field of tissue engineering and regenerative medicine has been evolving at a rapid pace
with numerous novel and interesting biomaterials being reported. Hydrogels have come a …

A myriad of pH-sensitive scaffolds has been reported in recent decades. Information on their
behaviour in vitro under conditions that mimic the pH changes that occur during tissue …

Repairing critical bone defects is a complex problem in the clinic. The periosteum rich in
nerve plays a vital role in initiating and regulating bone regeneration. However, current …

Reactive oxygen species (ROS) are important modulators of physiological signaling and
play important roles in bone tissue regulation. Both reactive sulfur species (RSS) and …

In view of their exceptional approach, excellent inherent biocompatibility and
biodegradability properties, and interaction with the local extracellular matrix, protein-based …

In vertebrates, bone is considered an osteoimmune system which encompasses functions of
a locomotive organ, a mineral reservoir, a hormonal organ, a stem cell pool and a cradle for …

Blood coagulation in tissue healing not only prevents blood loss, but also forms a natural
scaffold for tissue repair and regeneration. As blood clot formation is the initial and foremost …

Abstract Oxygen (O 2)-delivering tissue substitutes have shown tremendous potential for
enhancing tissue regeneration, maturation, and healing. As O 2 is both a metabolite and …

The gold standard treatment for anterior cruciate ligament (ACL) reconstruction is the use of
tendon autografts and allografts. Limiting factors for this treatment include donor site …