Neuraminidase is one of the two surface glycoproteins of influenza A and B viruses. It has
enzymatic activity that cleaves terminal sialic acid from glycans, and that activity is essential …

Influenza viruses have perplexed scientists for over a hundred years. Yearly vaccines limit
their spread, but they do not prevent all infections. Therapeutic treatments for those …

Natural killer (NK) cells are innate lymphoid cells, and their presence within human tumors
correlates with better prognosis. However, the mechanisms by which NK cells control tumors …

Lonicera japonica Thunb, rich in chlorogenic acid (CHA), is used for viral upper respiratory
tract infection treatment caused by influenza virus, parainfluenza virus, and respiratory …

Highlights•Broadly neutralizing antibodies against influenza A and B represents a safe and
affordable alternative to convalescent plasma.•The large majority of broadly neutralizing …

Abstract Scutellaria baicalensis Georgi, a Chinese herbal decoction, has been used for the
treatment of the common cold, fever and influenza virus infections. In previous studies, we …

Highlights•Host immune responses play both protective and pathogenic roles in IAV and
CoV infections.•Synergy of adaptive and innate immunity is required for efficient control of …

Broadly neutralizing antibodies (Abs) that bind the influenza virus hemagglutinin (HA) stem
may enable universal influenza vaccination. Here, we show that anti-stem Abs sterically …

Neuraminidase (NA) is an influenza surface protein that helps to free viruses from mucin-
associated decoy receptors and to facilitate budding from infected cells. Experiments have …

Natural Killer (NK) cells are potent cytotoxic cells belonging to the family of Innate Lymphoid
Cells (ILCs). Their most characterized effector functions are directed to the control of …