Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …

Besides its use for efficient production of recombinant proteins the methylotrophic yeast
Pichia pastoris (syn. Komagataella spp.) has been increasingly employed as a platform to …

NAD and NADP, a pivotal class of cofactors, which function as essential electron donors or
acceptors in all biological organisms, drive considerable catabolic and anabolic reactions …

Enzyme cascade catalysis has critical problems in obtaining the high concentrations of
products, such as the low stabilities and activities of biocatalysts and the inhibition by …

Abstract Background Pichia pastoris (Komagataella phaffii) is a model organism widely used
for the recombinant expression of eukaryotic proteins, and it can metabolize methanol as its …

Engineering Saccharomyces cerevisiae for industrial-scale production of valuable
chemicals involves extensive modulation of its metabolism. Here, we identified novel gene …

Biodiesel and biolubricants, derived from vegetable oils are substitutes for petroleum-
derived inputs and are already a global reality, with a possibility of enlarging their …

Glutathione (GSH) is a metabolite that plays an important role in the fields of pharmacy, food,
and cosmetics. Thus, it is necessary to increase its production to meet the demands. In this …

Pichia pastoris is a commonly used microbial host for recombinant protein production. It is
mostly cultivated in fed‐batch mode, in which the environment of the cell is continuously …

Background Pichia pastoris is a widely utilized host for heterologous protein expression and
biotransformation. Despite the numerous strategies developed to optimize the chassis host …