Following the success of recent endovascular trials, endovascular therapy has emerged as
an exciting addition to the arsenal of clinical management of patients with acute ischemic …

Recent advances in stroke reperfusion therapies have led to remarkable improvement in
clinical outcomes, but many patients remain severely disabled, due in part to the lack of …

2622 Stroke September 2017 cerebral edema and symptomatic intracranial hemorrhage,
which defines a malignant profile. 27 Because such patients have lowest rates of favorable …

All attempts at treating strokes by pharmacologically reducing the human brain's
vulnerability to ischaemia have failed, leaving stroke as a leading cause of death, disability …

Substantial experimental data and recent clinical evidence suggesting that tissue
reperfusion is a better predictor of outcome after thrombolysis than recanalization …

Background Stroke is a major cause of mortality and long-term disability worldwide. Whether
the associations between brain imaging-derived phenotypes (IDPs) and stroke are causal is …

Penumbra is the viable tissue around the irreversibly damaged ischemic core. The purpose
of acute stroke treatment is to salvage penumbral tissue and to improve brain function …

TP53-induced glycolysis and apoptosis regulator (TIGAR) alleviates oxidative stress and
protects against ischemic neuronal injury by shifting glucose metabolism into the pentose …

Futile recanalization hampers prognoses of ischemic stroke after successful mechanical
thrombectomy, hypothetically through post-recanalization perfusion deficits, onset-to-groin …

Gene transfection with Notch 1 intracellular domain and subsequent growth factor treatment
stimulate neuron-like differentiation of bone marrow stromal cells (BMSCs). Here, we …