Impacts of epigenetic processes on the health and productivity of livestock

M Wang, EM Ibeagha-Awemu - Frontiers in Genetics, 2021 - frontiersin.org
The dynamic changes in the epigenome resulting from the intricate interactions of genetic
and environmental factors play crucial roles in individual growth and development …

The epigenetics of gametes and early embryos and potential long-range consequences in livestock species—filling in the picture with epigenomic analyses

L Zhu, SL Marjani, Z Jiang - Frontiers in Genetics, 2021 - frontiersin.org
The epigenome is dynamic and forged by epigenetic mechanisms, such as DNA
methylation, histone modifications, chromatin remodeling, and non-coding RNA species …

Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting

X Lu, Y Zhang, L Wang, L Wang, H Wang, Q Xu… - Science …, 2021 - science.org
While mouse remains the most popular model, the conservation of parental-to-embryonic
epigenetic transition across mammals is poorly defined. Through analysis of oocytes and …

DNA methylation changes during preimplantation development reveal inter-species differences and reprogramming events at imprinted genes

E Ivanova, S Canovas, S Garcia-Martínez, R Romar… - Clinical …, 2020 - Springer
Preimplantation embryos experience profound resetting of epigenetic information inherited
from the gametes. Genome-wide analysis at single-base resolution has shown similarities …

Establishment of bovine trophoblast stem cells

Y Wang, H Ming, L Yu, J Li, L Zhu, HX Sun… - Cell Reports, 2023 - cell.com
Here, we report that a chemical cocktail (LCDM: leukemia inhibitory factor [LIF], CHIR99021,
dimethinedene maleate [DiM], minocycline hydrochloride), previously developed for …

Sperm DNA methylation patterns at discrete CpGs and genes involved in embryonic development are related to bull fertility

M Štiavnická, A Chaulot-Talmon, JP Perrier, P Hošek… - BMC genomics, 2022 - Springer
Background Despite a multifactorial approach being taken for the evaluation of bull semen
quality in many animal breeding centres worldwide, reliable prediction of bull fertility is still a …

Third-generation sequencing reveals the adaptive role of the epigenome in three deep-sea polychaetes

M Perez, O Aroh, Y Sun, Y Lan… - Molecular Biology …, 2023 - academic.oup.com
The roles of DNA methylation in invertebrates are poorly characterized, and critical data are
missing for the phylum Annelida. We fill this knowledge gap by conducting the first genome …

The landscape of accessible chromatin in bovine oocytes and early embryos

H Ming, J Sun, R Pasquariello, L Gatenby, JR Herrick… - Epigenetics, 2021 - Taylor & Francis
Chromatin reorganization governs the regulation of gene expression during preimplantation
development. However, the landscape of chromatin dynamics in this period has not been …

Comparative whole genome DNA methylation profiling across cattle tissues reveals global and tissue-specific methylation patterns

Y Zhou, S Liu, Y Hu, L Fang, Y Gao, H Xia… - BMC biology, 2020 - Springer
Background Efforts to improve animal health, and understand genetic bases for production,
may benefit from a comprehensive analysis of animal genomes and epigenomes. Although …

Maternal restricted-and over-feeding during gestation perturb offspring sperm epigenome in sheep

L Zhu, N Tillquist, G Scatolin, R Gately… - …, 2023 - rep.bioscientifica.com
In brief Inadequate maternal nutrition during gestation can have immediate and lifelong
effects on offspring. This study shows that maternal restricted-and over-nutrition during …