The multirole of liposomes in therapy and prevention of infectious diseases

R Nisini, N Poerio, S Mariotti, F De Santis… - Frontiers in …, 2018 - frontiersin.org
Liposomes are closed bilayer structures spontaneously formed by hydrated phospholipids
that are widely used as efficient delivery systems for drugs or antigens, due to their capability …

Structure and function of TMEM16 proteins (anoctamins)

N Pedemonte, LJV Galietta - Physiological reviews, 2014 - journals.physiology.org
TMEM16 proteins, also known as anoctamins, are involved in a variety of functions that
include ion transport, phospholipid scrambling, and regulation of other membrane proteins …

Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells

JE Vance, G Tasseva - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2013 - Elsevier
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related
membrane aminophospholipids. In mammalian cells, PS is required for targeting and …

[HTML][HTML] Curvature, lipid packing, and electrostatics of membrane organelles: defining cellular territories in determining specificity

J Bigay, B Antonny - Developmental cell, 2012 - cell.com
Whereas some rare lipids contribute to the identity of cell organelles, we focus on the
abundant lipids that form the matrix of organelle membranes. Observations using bioprobes …

Cryptococcus neoformans adapts to the host environment through TOR-mediated remodeling of phospholipid asymmetry

LC Ristow, AJ Jezewski, BJ Chadwick… - Nature …, 2023 - nature.com
Cryptococcus spp. are environmental fungi that first must adapt to the host environment
before they can cause life-threatening meningitis in immunocompromised patients. Host …

The distribution and function of phosphatidylserine in cellular membranes

PA Leventis, S Grinstein - Annual review of biophysics, 2010 - annualreviews.org
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in
eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma …

Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine

J Durgan, AH Lystad, K Sloan, SR Carlsson, MI Wilson… - Molecular cell, 2021 - cell.com
Autophagy is a fundamental catabolic process that uses a unique post-translational
modification, the conjugation of ATG8 protein to phosphatidylethanolamine (PE). ATG8 …

Phospholipid subcellular localization and dynamics

Y Yang, M Lee, GD Fairn - Journal of Biological Chemistry, 2018 - ASBMB
Membrane biology seeks to understand how lipids and proteins within bilayers assemble
into large structures such as organelles and the plasma membranes. Historically, lipids were …

Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration

T Banerjee, D Biswas, DS Pal, Y Miao, PA Iglesias… - Nature cell …, 2022 - nature.com
During cell migration and polarization, numerous signal transduction and cytoskeletal
components self-organize to generate localized protrusions. Although biochemical and …

Phagosome dynamics during phagocytosis by neutrophils

P Nordenfelt, H Tapper - Journal of leukocyte biology, 2011 - academic.oup.com
The neutrophil is a key player in immunity, and its activities are essential for the resolution of
infections. Neutrophil-pathogen interactions usually trigger a large arsenal of antimicrobial …