The impact of Nrf2/HO-1, caspase-3/Bax/Bcl2 and ATF6/IRE1/PERK/GRP78 signaling pathways in the ameliorative effects of morin against methotrexate-induced …
Background Methotrexate (MT) is a broadly used chemotherapeutic drug however its clinical
use is confronted with several forms of toxicities containing testicular damage. The current …
use is confronted with several forms of toxicities containing testicular damage. The current …
The prospects for the use of vitamin B12 derivatives in pharmacology
IY Torshin, OA Gromova… - FARMAKOEKONOMIKA …, 2023 - pharmacoeconomics.ru
Background. The structure of corrin tetrapyrrole macrocycles (compounds similar in structure
to vitamin B12) is a kind of universal chemical template for targeted drug delivery, and the …
to vitamin B12) is a kind of universal chemical template for targeted drug delivery, and the …
[HTML][HTML] Role of Vitamin C on methotrexate-induced nephrotoxicity in psoriasis context: A preclinical assessment
EN Díaz-de-la-Cruz, GE Hurtado-Nuñez… - Toxicology Reports, 2024 - Elsevier
Methotrexate (MTX) is the most prescribed drug for systemic treatment of psoriasis.
However, its clinical use is limited by its nephrotoxicity, which antioxidants can attenuate …
However, its clinical use is limited by its nephrotoxicity, which antioxidants can attenuate …
Biochemical, Immunohistochemical, Histopathological, and Apoptotic Evaluation of Nickel Oxide Nanoparticle-and Microparticle-Induced Testicular Toxicity in Male …
C Adiguzel, H Karaboduk - ACS omega, 2024 - ACS Publications
Nickel oxide nanoparticles are engineered particles that are now widely used in medicine,
agriculture, and industry applications. This study aimed to investigate subchronic testicular …
agriculture, and industry applications. This study aimed to investigate subchronic testicular …
The Role of Cobalamin in Multiple Sclerosis: An Update
M Golabi, D Kazemi, AS Chadeganipour… - Inflammation, 2024 - Springer
Multiple sclerosis (MS) is a neurodegenerative condition that results in axonal and
permanent damage to the central nervous system, necessitating healing owing to …
permanent damage to the central nervous system, necessitating healing owing to …
[HTML][HTML] Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats
Objective (s): Methotrexate (MTX) is a drug with anti-inflammatory and immunosuppressive
effects and is also a folic acid antagonist. Our aim in this study is to determine the molecular …
effects and is also a folic acid antagonist. Our aim in this study is to determine the molecular …
The effects of morin and methotrexate on pentose phosphate pathway enzymes and GR/GST/TrxR enzyme activities: An in vivo and in silico study
In this study, the mechanisms by which the enzymes glucose‐6‐phosphate dehydrogenase
(G6PD), 6‐phosphogluconate dehydrogenase (6PGD), glutathione reductase (GR) …
(G6PD), 6‐phosphogluconate dehydrogenase (6PGD), glutathione reductase (GR) …
Alamandine alleviates methotrexate-induced nephrotoxicity in rats by targeting oxidative stress and inflammation
Aim: Nephrotoxicity due to the use of methotrexate (Mtx) is one of the most important
problems associated with chemotherapy. Oxidative stress and inflammation are the major …
problems associated with chemotherapy. Oxidative stress and inflammation are the major …
Gentamisin kullanımına bağlı gelişen nefrotoksisitede b12 vitamininin etkilerinin araştırılması
M Çelebi - 2024 - search.proquest.com
Aminoglikozid grubu antibiyotiklerin kullanımına bağlı olarak% 10-25 oranında nefrotoksisite
gelişme ihtimali vardır. Aminoglikozid kullanımına bağlı nefrotoksisiteye karşı rutin olarak …
gelişme ihtimali vardır. Aminoglikozid kullanımına bağlı nefrotoksisiteye karşı rutin olarak …