[HTML][HTML] Recent developments in synthetic chemistry and biological activities of pyrazole derivatives
Pyrazole, a five-membered heterocycle containing two nitrogen atoms, is extensively found
as a core framework in a huge library of heterocyclic compounds that envelops promising …
as a core framework in a huge library of heterocyclic compounds that envelops promising …
Current progress on antioxidants incorporating the pyrazole core
VLM Silva, J Elguero, AMS Silva - European journal of medicinal chemistry, 2018 - Elsevier
The search of new antioxidants, as drugs candidates, is an active field of medicinal
chemistry. The synthesis of compounds with antioxidant potential has increased in recent …
chemistry. The synthesis of compounds with antioxidant potential has increased in recent …
Recent progress in anticancer agents incorporating pyrazole scaffold
S Mor, M Khatri, S Sindhu - Mini Reviews in Medicinal …, 2022 - ingentaconnect.com
The search for new anticancer agents is considered a dynamic field of medicinal chemistry.
In recent years, the synthesis of compounds with anticancer potential has increased and a …
In recent years, the synthesis of compounds with anticancer potential has increased and a …
[PDF][PDF] A review on Pyrazole derivatives of pharmacological potential
A Jamwal, A Javed, V Bhardwaj - J. Pharm. BioSci, 2013 - speronline.com
Pyrazole is five membered heterocyclic rings which is versatile lead compound for designing
potent bioactive agent. The interesting groups of this compound has diverse biological …
potent bioactive agent. The interesting groups of this compound has diverse biological …
The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review.
Pyrazole nucleus is a unique structural scaffold which acts as an interesting template for
combinatorial as well as medicinal chemistry. This review presents a detailed overview on …
combinatorial as well as medicinal chemistry. This review presents a detailed overview on …
[HTML][HTML] Potential anti-inflammatory effect of LQFM-021 in carrageenan-induced inflammation: the role of nitric oxide
IF Florentino, DPB Silva, DM Silva, CS Cardoso… - Nitric Oxide, 2017 - Elsevier
The pyrazole compound LQFM-021 exhibits vasorelaxant, antinociceptive and anti-
inflammatory activities. Furthermore, it has low toxicity, indicating that this compound may be …
inflammatory activities. Furthermore, it has low toxicity, indicating that this compound may be …
Analgesic and Antipyretic Activities of Ethyl Acetate Fraction Tablet of Andrographis paniculata in Animal Models
Objectives. To determine the analgesic and antipyretic activities of a tablet derived from
Andrographis paniculata ethyl acetate fraction (AS201‐01) in animal models. Methods. The …
Andrographis paniculata ethyl acetate fraction (AS201‐01) in animal models. Methods. The …
Antinociceptive effect of 3-(4-fluorophenyl)-5-trifluoromethyl-1H-1-tosylpyrazole. A Celecoxib structural analog in models of pathological pain
SM Oliveira, CR Silva, AP Wentz, GR Paim… - Pharmacology …, 2014 - Elsevier
Pain is the most common complaint in the medical field and the identification of novel
compounds that can effectively treat painful states without causing side effects remains a …
compounds that can effectively treat painful states without causing side effects remains a …
[HTML][HTML] An Unusual Rearrangement of Pyrazole Nitrene and Coarctate Ring-Opening/Recyclization Cascade: Formal CH–Acetoxylation and Azide/Amine Conversion …
E Chugunova, AS Gazizov, D Islamov, V Matveeva… - Molecules, 2023 - mdpi.com
We report an unusual transformation where the transient formation of a nitrene moiety
initiates a sequence of steps leading to remote oxidative C–H functionalization (R–CH3 to R …
initiates a sequence of steps leading to remote oxidative C–H functionalization (R–CH3 to R …
Design, synthesis of tri‐substituted pyrazole derivatives as promising antimicrobial agents and investigation of structure activity relationships
The major diseases spread in the environment only because of microbes. Even, intensive
care units in the hospitals are polluted by microorganisms, particularly, Gram‐positive …
care units in the hospitals are polluted by microorganisms, particularly, Gram‐positive …