Alagille syndrome (ALGS) is an autosomal dominant disorder, with multisystem involvement,
which usually occurs due to Notch signaling pathway defects, mostly due to JAG1 mutation …

Xanthogranulomatous osteomyelitis (XO) is an exceedingly rare disease characterized by
infiltration of histiocytes and foamy macrophages. Both on gross examination and on …

Background Alagille syndrome (ALGS) is a rare multisystem disorder caused by mutations in
the JAG1 or NOTCH2 gene. However NOTCH2 gene mutations were rarely found in the …

Objective: Unusual clinical course Background: Alagille syndrome (ALGS) is a multisystem
hereditary illness with a dominant pattern and partial penetrance. Multiple organ …

This article is the ninth in a series on the biological basis of child health and follows on from
the previous article, which discussed the gastrointestinal system. The liver is the largest solid …

Background: Alagille syndrome (ALGS) is an autosomal dominant disease caused by JAG1
or NOTCH2 mutation. It is diagnosed by the presence of three out of five features …

Alagille syndrome (ALGS) is a genetic-driven condition of chronic cholestasis, involving the
intrahepatic bile ducts, heart, vessels, kidneys, skeletal tissues, eyes, and nervous system …

Alagille syndrome is a rare and complex pleiotropic multisystem disorder caused by an
autosomal dominant genetic mutation of JAG1 (90%) and NOTCH2 (1%–2%) genes located …

Sir, Alagille syndrome (AGS) is a rare autosomal dominant disorder, with multisystem
involvement reported almost exclusively in early infancy or the paediatric age group. Cases …

Alagille syndrome (ALGS) is a complex multi-systemic genetic disorder which involves
primarily the liver, heart, eyes, face, and skeletal structure. The purpose of the work is to …