Over the past two decades, compelling evidence has emerged indicating that immune
mechanisms can contribute to the pathogenesis of major depressive disorder (MDD) and …

BackgroundPeripheral low-grade inflammation in depression is increasingly seen as a
therapeutic target. We aimed to establish the prevalence of low-grade inflammation in …

Background Schizophrenia (SCZ) is a severe psychiatric disorder that involves inflammatory
processes. The aim of this study was to explore the field of inflammation-related research in …

The vagus nerve represents the main component of the parasympathetic nervous system,
which oversees a vast array of crucial bodily functions, including control of mood, immune …

The study of the gut microbiome has increasingly revealed an important role in modulating
brain function and mental health. In this review, we underscore specific pathways and …

Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …

Abstract Social Signal Transduction Theory of Depression is a biologically plausible, multi-
level theory that describes neural, physiologic, molecular, and genomic mechanisms that …

Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders.
Pathological mechanisms are still vastly unclear, and current treatments with conventional …

Background No study has gathered evidence from all randomized clinical trials (RCT s) with
anti‐inflammatory drugs measuring antidepressant effects including a detailed assessment …

The gut-brain axis is a bidirectional communication network that links the enteric and central
nervous systems. This network is not only anatomical, but it extends to include endocrine …