Noble metals in medicine: Latest advances
History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …
ancient times. For example, silver was employed in the treatment of wounds and ulcers …
Alternative technologies that facilitate access to discrete metal complexes
A Beillard, X Bantreil, TX Métro, J Martinez… - Chemical …, 2019 - ACS Publications
Organometallic complexes: these two words jump to the mind of the chemist and are directly
associated with their utility in catalysis or as a pharmaceutical. Nevertheless, to be able to …
associated with their utility in catalysis or as a pharmaceutical. Nevertheless, to be able to …
The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways
X Mi, J Hou, Z Wang, Y Han, S Ren, J Hu, C Chen… - Scientific reports, 2018 - nature.com
Cisplatin, a potent anticancer drug, is usually causing nephrotoxicity; limiting its therapeutic
application and efficiency. Maltol may be used to prevent such toxic effect. The aim of this …
application and efficiency. Maltol may be used to prevent such toxic effect. The aim of this …
Maltol, a food flavoring agent, attenuates acute alcohol-induced oxidative damage in mice
Y Han, Q Xu, J Hu, X Han, W Li, L Zhao - Nutrients, 2015 - mdpi.com
The purpose of this study was to evaluate the hepatoprotective effect of maltol, a food-
flavoring agent, on alcohol-induced acute oxidative damage in mice. Maltol used in this …
flavoring agent, on alcohol-induced acute oxidative damage in mice. Maltol used in this …
Metal Complexes in cancer treatment: Journey so far
A Kumar Singh, A Kumar, H Singh… - Chemistry & …, 2023 - Wiley Online Library
Metal complexes in cancer therapy have attracted much interest mainly because metals
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …
Evaluation of in vitro distribution and plasma protein binding of selected antiviral drugs (favipiravir, molnupiravir and imatinib) against SARS-CoV-2
There are a number of uncertainties regarding plasma protein binding and blood distribution
of the active drugs favipiravir (FAVI), molnupiravir (MOLNU) and imatinib (IMA), which were …
of the active drugs favipiravir (FAVI), molnupiravir (MOLNU) and imatinib (IMA), which were …
Arene–Arene Coupled Disulfamethazines (or Sulfadiazine)-Phenanthroline-Metal (II) Complexes were Synthesized by In Situ Reactions and Inhibited the Growth and …
BB Xu, N Jin, JC Liu, AQ Liao, HY Lin… - Journal of Medicinal …, 2024 - ACS Publications
The novel metal (II)-based complexes HA-Cu, HA-Co, and HA-Ni with phenanthroline,
sulfamethazine, and aromatic–aromatic coupled disulfamethazines as ligands were …
sulfamethazine, and aromatic–aromatic coupled disulfamethazines as ligands were …
Binding mechanisms of half-sandwich Rh (III) and Ru (II) arene complexes on human serum albumin: A comparative study
Various half-sandwich ruthenium (II) arene complexes and rhodium (III) arene complexes
have been intensively investigated due to their prominent anticancer activity. The interaction …
have been intensively investigated due to their prominent anticancer activity. The interaction …
Anticancer half-sandwich rhodium (III) complexes
Platinum-based anticancer drugs are most likely the most successful group of bioinorganic
compounds. Their apparent disadvantages have led to the development of anticancer …
compounds. Their apparent disadvantages have led to the development of anticancer …
The liver protection effects of maltol, a flavoring agent, on carbon tetrachloride-induced acute liver injury in mice via inhibiting apoptosis and inflammatory response
W Liu, Z Wang, J Hou, Y Zhou, Y He, S Jiang, Y Wang… - Molecules, 2018 - mdpi.com
The purpose of this research was to evaluate whether maltol could protect from hepatic
injury induced by carbon tetrachloride (CCl4) in vivo by inhibition of apoptosis and …
injury induced by carbon tetrachloride (CCl4) in vivo by inhibition of apoptosis and …