Extracellular matrix–based biomaterials for cardiac regeneration and repair

H Li, M Bao, Y Nie - Heart failure reviews, 2021 - Springer
The spectrum of ischemic heart diseases, encompassing acute myocardial infarction to heart
failure, represents the leading cause of death worldwide. Although extensive progress in …

Current perspectives on biological approaches for osteoarthritis

KE Whitney, A Liebowitz, IK Bolia… - Annals of the New …, 2017 - Wiley Online Library
Musculoskeletal injuries that disrupt the structure and function of diarthrodial joints can
cause permanent biomechanical alterations and lead to a more severe, chronic condition …

3D-printed vascular networks direct therapeutic angiogenesis in ischaemia

T Mirabella, JW MacArthur, D Cheng… - Nature biomedical …, 2017 - nature.com
Arterial bypass grafts remain the gold standard for the treatment of end-stage ischaemic
disease. Yet patients unable to tolerate the cardiovascular stress of arterial surgery or those …

Functional engineered human cardiac patches prepared from nature's platform improve heart function after acute myocardial infarction

Q Wang, H Yang, A Bai, W Jiang, X Li, X Wang, Y Mao… - Biomaterials, 2016 - Elsevier
With the advent of induced pluripotent stem cells and directed differentiation techniques, it is
now feasible to derive individual-specific cardiac cells for human heart tissue engineering …

A novel protein‐engineered hepatocyte growth factor analog released via a shear‐thinning injectable hydrogel enhances post‐infarction ventricular function

AN Steele, L Cai, VN Truong… - Biotechnology and …, 2017 - Wiley Online Library
In the last decade, numerous growth factors and biomaterials have been explored for the
treatment of myocardial infarction (MI). While pre‐clinical studies have demonstrated …

Natural cardiac regeneration conserves native biaxial left ventricular biomechanics after myocardial infarction in neonatal rats

H Wang, A Wisneski, AM Imbrie-Moore… - Journal of the …, 2022 - Elsevier
After myocardial infarction (MI), adult mammals exhibit scar formation, adverse left
ventricular (LV) remodeling, LV stiffening, and impaired contractility, ultimately resulting in …

Exceptional biocompatibility of 3D fibrous scaffold for cardiac tissue engineering fabricated from biodegradable polyurethane blended with cellulose

WF Su, CC Ho, TH Shih, CH Wang… - International Journal of …, 2016 - Taylor & Francis
The auhtors report 3D biomimetic scaffolds using polymer blend of polyurethane and
cellulose for cardiac tissue engineering. The biocompatible and biodegradable …

Multiaxial lenticular stress-strain relationship of native myocardium is preserved by infarct-induced natural heart regeneration in neonatal mice

H Wang, R Bennett-Kennett, MJ Paulsen… - Scientific Reports, 2020 - nature.com
Neonatal mice exhibit natural heart regeneration after myocardial infarction (MI) on postnatal
day 1 (P1), but this ability is lost by postnatal day 7 (P7). Cardiac biomechanics intricately …

Collagen-supplemented incubation rapidly augments mechanical property of fibroblast cell sheets

Y Zhu, AD Thakore, JM Farry, J Jung… - … Engineering Part A, 2021 - liebertpub.com
Cell sheet technology using UpCell™(Thermo Fisher Scientific, Roskilde, Denmark) plates
is a modern tool that enables the rapid creation of single-layered cells without using …

Dual Enzyme Sequential Digestion Protocol for Isolation of Human Primary Chondrocytes From the Articular Cartilage Derived From Knee Osteoarthritis Patients

AK Anuja, MK Rai, L Gupta, N Nigam… - Indian Journal of …, 2024 - journals.sagepub.com
Introduction: Majority of available protocols for isolation of chondrocytes from articular
cartilage tissue rely on the enzymatic digestion of the tissue by collagenase type 2. The yield …