We present in this paper a picture of the neural systems controlling defense that updates
and simplifies Gray's “Neuropsychology of Anxiety”. It is based on two behavioural …

The contribution of glutamate to synaptic transmission, plasticity and development is well
established; current evidence is based on diverse approaches to decipher function and …

RECEPTORS for N-methyl-d-aspartate (NMDA) seem to have a critical role in synaptic
plasticity1–4. NMDA antagonists (such as AP5) prevent induction of long-term potentiation5 …

There has recently been renewed interest in the idea that alterations in synaptic efficacy may
be the neural basis of information storage. Particular attention has been focused upon long …

The aim of the present study was to investigate the effects of NMDA receptor blockade on
formation of object recognition memory. In the first experiment, adult Wistar rats were given …

Personality factors, as normally studied, are sources of variation that are stable over time
and that derive from underlying properties of an individual more than current changes in …

Anandamine (arachidonylethanolamide), an arachidonic acid derivative isolated from the
porcine brain, displays binding characteristics indicative of an endogenous ligand for the …

A great body of evidence has been provided for the role of N-methyl-D-aspartate (NMDA)
receptors in learning processes, since the pioneering work of Morris el al.(1986) showing …

On the occasion of the 40 year anniversary of the hugely impactful review by Richard (Dick)
Evans and Jeff Watkins, we describe how their work has impacted the field of synaptic …

The dose-and time-dependent effects of N-methyl-D-aspartate receptor/channel antagonists
on radial 8-arm maze performance were examined in rats. Both CPP (1.0–30 mg/kg), a …