[HTML][HTML] Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering

E Hasanzadeh, A Seifalian, A Mellati, J Saremi… - Materials Today Bio, 2023 - Elsevier
Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover
after damage. A clinically acceptable treatment to promote CNS functional recovery and …

From basics to clinical: a comprehensive review on spinal cord injury

NA Silva, N Sousa, RL Reis, AJ Salgado - Progress in neurobiology, 2014 - Elsevier
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

[HTML][HTML] A review of natural polysaccharides for drug delivery applications: Special focus on cellulose, starch and glycogen

V Gopinath, S Saravanan, AR Al-Maleki… - Biomedicine & …, 2018 - Elsevier
Natural polysaccharides are renewable with a high degree of biocompatibility,
biodegradability, and ability to mimic the natural extracellular matrix (ECM) …

Regenerative therapies for spinal cord injury

N Ashammakhi, HJ Kim, A Ehsanipour… - … Engineering Part B …, 2019 - liebertpub.com
Spinal cord injury (SCI) is a serious problem that primarily affects younger and middle-aged
adults at its onset. To date, no effective regenerative treatment has been developed. Over …

Current options for cell therapy in spinal cord injury

I Vismara, S Papa, F Rossi, G Forloni… - Trends in molecular …, 2017 - cell.com
Spinal cord injury (SCI) is a complex pathology that evolves after primary acute mechanical
injury, causing further damage to the spinal cord tissue that exacerbates clinical outcomes …

Minimally invasive and regenerative therapeutics

N Ashammakhi, S Ahadian, MA Darabi… - Advanced …, 2019 - Wiley Online Library
Advances in biomaterial synthesis and fabrication, stem cell biology, bioimaging,
microsurgery procedures, and microscale technologies have made minimally invasive …

Hydrogels and cell based therapies in spinal cord injury regeneration

RC Assunção-Silva, ED Gomes, N Sousa… - Stem cells …, 2015 - Wiley Online Library
Spinal cord injury (SCI) is a central nervous system‐(CNS‐) related disorder for which there
is yet no successful treatment. Within the past several years, cell‐based therapies have …

Designer, injectable gels to prevent transplanted Schwann cell loss during spinal cord injury therapy

LM Marquardt, VM Doulames, AT Wang, K Dubbin… - Science …, 2020 - science.org
Transplantation of patient-derived Schwann cells is a promising regenerative medicine
therapy for spinal cord injuries; however, therapeutic efficacy is compromised by inefficient …

Injectable hydrogels for central nervous system therapy

MM Pakulska, BG Ballios, MS Shoichet - Biomedical materials, 2012 - iopscience.iop.org
Diseases and injuries of the central nervous system (CNS) including those in the brain,
spinal cord and retina are devastating because the CNS has limited intrinsic regenerative …

Remote and local control of stimuli responsive materials for therapeutic applications

A Chan, RP Orme, RA Fricker, P Roach - Advanced drug delivery reviews, 2013 - Elsevier
Materials offering the ability to change their characteristics in response to presented stimuli
have demonstrated application in the biomedical arena, allowing control over drug delivery …