[HTML][HTML] The noncoding RNA revolution—trashing old rules to forge new ones
TR Cech, JA Steitz - Cell, 2014 - cell.com
Noncoding RNAs (ncRNAs) accomplish a remarkable variety of biological functions. They
regulate gene expression at the levels of transcription, RNA processing, and translation …
regulate gene expression at the levels of transcription, RNA processing, and translation …
Dosage compensation in Drosophila melanogaster: epigenetic fine-tuning of chromosome-wide transcription
Dosage compensation is an epigenetic mechanism that normalizes gene expression from
unequal copy numbers of sex chromosomes. Different organisms have evolved alternative …
unequal copy numbers of sex chromosomes. Different organisms have evolved alternative …
The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator
J Feng, C Bi, BS Clark, R Mady, P Shah… - Genes & …, 2006 - genesdev.cshlp.org
The identification of ultraconserved noncoding sequences in vertebrates has been
associated with developmental regulators and DNA-binding proteins. One of the first of …
associated with developmental regulators and DNA-binding proteins. One of the first of …
[HTML][HTML] Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation
E Heard, C Rougeulle, D Arnaud, P Avner, CD Allis… - Cell, 2001 - cell.com
Coating of the X chromosome by Xist RNA is an essential trigger for X inactivation. However,
little is known about the early chromatin remodeling events that transform this signal into …
little is known about the early chromatin remodeling events that transform this signal into …
A kinetic framework for a mammalian RNA polymerase in vivo
M Dundr, U Hoffmann-Rohrer, Q Hu, I Grummt… - Science, 2002 - science.org
We have analyzed the kinetics of assembly and elongation of the mammalian RNA
polymerase I complex on endogenous ribosomal genes in the nuclei of living cells with the …
polymerase I complex on endogenous ribosomal genes in the nuclei of living cells with the …
A mechanical basis for chromosome function
N Kleckner, D Zickler, GH Jones… - Proceedings of the …, 2004 - National Acad Sciences
A mechanical basis for chromosome function | PNAS PNAS Logo PNAS Logo ARTICLES Current
IssueLatest ArticlesSpecial FeaturesList of IssuesPNAS Nexus Front Matter AUTHORS …
IssueLatest ArticlesSpecial FeaturesList of IssuesPNAS Nexus Front Matter AUTHORS …
Drosophila dosage compensation: a complex voyage to the X chromosome
ME Gelbart, MI Kuroda - 2009 - journals.biologists.com
Dosage compensation is the crucial process that equalizes gene expression from the X
chromosome between males (XY) and females (XX). In Drosophila, the male-specific lethal …
chromosome between males (XY) and females (XX). In Drosophila, the male-specific lethal …
[HTML][HTML] A sequence motif within chromatin entry sites directs MSL establishment on the Drosophila X chromosome
The Drosophila MSL complex associates with active genes specifically on the male X
chromosome to acetylate histone H4 at lysine 16 and increase expression approximately 2 …
chromosome to acetylate histone H4 at lysine 16 and increase expression approximately 2 …
[HTML][HTML] The roX genes encode redundant male‐specific lethal transcripts required for targeting of the MSL complex
VH Meller, BP Rattner - The EMBO journal, 2002 - embopress.org
The roX1 and roX2 genes of Drosophila produce male‐specific non‐coding RNAs that co‐
localize with the Male‐Specific Lethal (MSL) protein complex. This complex mediates up …
localize with the Male‐Specific Lethal (MSL) protein complex. This complex mediates up …
Chromatin remodeling in dosage compensation
JC Lucchesi, WG Kelly, B Panning - Annu. Rev. Genet., 2005 - annualreviews.org
In many multicellular organisms, males have one X chromosome and females have two.
Dosage compensation refers to a regulatory mechanism that insures the equalization of X …
Dosage compensation refers to a regulatory mechanism that insures the equalization of X …