DNA secondary structures: stability and function of G-quadruplex structures
ML Bochman, K Paeschke, VA Zakian - Nature Reviews Genetics, 2012 - nature.com
In addition to the canonical double helix, DNA can fold into various other inter-and
intramolecular secondary structures. Although many such structures were long thought to be …
intramolecular secondary structures. Although many such structures were long thought to be …
Mechanisms of binding specificity among bHLH transcription factors
The transcriptome of every cell is orchestrated by the complex network of interaction
between transcription factors (TFs) and their binding sites on DNA. Disruption of this network …
between transcription factors (TFs) and their binding sites on DNA. Disruption of this network …
[HTML][HTML] Global regulation of promoter melting in naive lymphocytes
F Kouzine, D Wojtowicz, A Yamane, W Resch… - Cell, 2013 - cell.com
Lymphocyte activation is initiated by a global increase in messenger RNA synthesis.
However, the mechanisms driving transcriptome amplification during the immune response …
However, the mechanisms driving transcriptome amplification during the immune response …
Myogenic differentiation of stem cells for skeletal muscle regeneration
D Yu, Z Cai, D Li, Y Zhang, M He, Y Yang… - Stem Cells …, 2021 - Wiley Online Library
Stem cells have become a hot research topic in the field of regenerative medicine due to
their self‐renewal and differentiation capabilities. Skeletal muscle tissue is one of the most …
their self‐renewal and differentiation capabilities. Skeletal muscle tissue is one of the most …
Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential
ABSTRACT The human Werner and Bloom syndromes (WS and BS) are caused by
deficiencies in the WRN and BLM RecQ helicases, respectively. WRN, BLM and their …
deficiencies in the WRN and BLM RecQ helicases, respectively. WRN, BLM and their …
Evidence of genome-wide G4 DNA-mediated gene expression in human cancer cells
Guanine-rich DNA of a particular sequence adopts four-stranded structural forms known as
G-quadruplex or G4 DNA. Though in vitro formation of G4 DNA is known for several years, in …
G-quadruplex or G4 DNA. Though in vitro formation of G4 DNA is known for several years, in …
Genome-wide study predicts promoter-G4 DNA motifs regulate selective functions in bacteria: radioresistance of D. radiodurans involves G4 DNA-mediated …
A remarkable number of guanine-rich sequences with potential to adopt non-canonical
secondary structures called G-quadruplexes (or G4 DNA) are found within gene promoters …
secondary structures called G-quadruplexes (or G4 DNA) are found within gene promoters …
MiR-17 and miR-19 cooperatively promote skeletal muscle cell differentiation
D Kong, M He, L Yang, R Zhou, YQ Yan… - Cellular and Molecular …, 2019 - Springer
Skeletal myogenesis is a highly coordinated process that involves cell proliferation,
differentiation and fusion controlled by a complex gene regulatory network. The microRNA …
differentiation and fusion controlled by a complex gene regulatory network. The microRNA …
The evolving world of protein-G-quadruplex recognition: a medicinal chemist's perspective
C Sissi, B Gatto, M Palumbo - Biochimie, 2011 - Elsevier
The physiological and pharmacological role of nucleic acids structures folded into the non
canonical G-quadruplex conformation have recently emerged. Their activities are targeted at …
canonical G-quadruplex conformation have recently emerged. Their activities are targeted at …
Homodimeric and heterodimeric interactions among vertebrate basic helix–loop–helix transcription factors
AL Torres-Machorro - International Journal of Molecular Sciences, 2021 - mdpi.com
The basic helix–loop–helix transcription factor (bHLH TF) family is involved in tissue
development, cell differentiation, and disease. These factors have transcriptionally positive …
development, cell differentiation, and disease. These factors have transcriptionally positive …