In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

Purpose Advancing maternal and paternal age leads to a decrease in fertility, and hence,
many infertile couples opt for assisted reproductive technologies [ART] to achieve biological …

Multiple changes occur across various endocrine systems as an individual ages. The
understanding of the factors that cause age-related changes and how they should be …

Adverse experiences in early life are risk factors for the development of behavioral and
physiological symptoms that can lead to psychiatric and cognitive disorders later in life …

STUDY QUESTION What is the semen quality of young adult men who were conceived 18–
22 years ago by ICSI for male infertility? SUMMARY ANSWER In this cohort of 54 young …

Male germ cells undergo an extreme but fascinating process of chromatin remodeling that
begins in the testis during the last phase of spermatogenesis and continues through …

The spermatozoon is a highly differentiated and polarized cell, with two main structures: the
head, containing a haploid nucleus and the acrosomal exocytotic granule, and the flagellum …

Infertility is an often devastating diagnosis encountered by around one in six couples who
are trying to conceive. Moving away from the long-held belief that infertility is primarily a …

Life‐long sperm production leads to the assumption that male fecundity remains unchanged
throughout life. However, recently it was shown that paternal age has profound …

Infertility is a significant problem for human reproduction, with males and females equally
affected. However, the molecular mechanisms underlying male infertility remain unclear …