Recent advances in the determination of elemental impurities in pharmaceuticals–Status, challenges and moving frontiers

V Balaram - Trac trends in Analytical chemistry, 2016 - Elsevier
Elemental impurities have been regulated in pharmaceutical products for many decades.
Metal impurities such as As, Cd, Cu, Pb, Hg, V and Pt in pharmaceuticals and drugs are …

An overview of recent applications of inductively coupled plasma-mass spectrometry (ICP-MS) in determination of inorganic impurities in drugs and pharmaceuticals

RN Rao, MVNK Talluri - Journal of pharmaceutical and biomedical …, 2007 - Elsevier
The recent applications of inductively coupled plasma-mass spectrometry (ICP-MS) in
determination of trace level inorganic impurities in drugs and pharmaceuticals have been …

Metal impurities in food and drugs

DR Abernethy, AJ DeStefano, TL Cecil, K Zaidi… - Pharmaceutical …, 2010 - Springer
The major metals of potential health concern found in food, drugs (medicines), and dietary
supplements are lead, cadmium, mercury, and arsenic. Other metals, such as chromium …

A rapid ICP-MS screen for heavy metals in pharmaceutical compounds

N Lewen, S Mathew, M Schenkenberger… - … of pharmaceutical and …, 2004 - Elsevier
A robust general inductively coupled plasma-mass spectrometry (ICP-MS) based method
was developed as an alternative to the wet chemical heavy metals test prescribed in the …

An “off–on” rhodamine 6G hydrazide-based output platform for fluorescence and visual dual-mode detection of lead (II)

X Xie, M Pan, L Hong, K Liu, J Yang… - Journal of Agricultural …, 2021 - ACS Publications
In this study, the rhodamine 6G hydrazide (R6GH) complex was synthesized to develop an
“off–on” output platform for fluorescence and visual dual-mode analysis of lead (II)(Pb2+) …

The use of atomic spectroscopy in the pharmaceutical industry for the determination of trace elements in pharmaceuticals

N Lewen - Journal of pharmaceutical and biomedical analysis, 2011 - Elsevier
The subject of the analysis of various elements, including metals and metalloids, in the
pharmaceutical industry has seen increasing importance in the last 10–15 years, as modern …

Heavy metal ion detection with Nano-Engineered Materials: Scaling down for precision

P Dey, M Kaur, A Khajuria, D Kaur, M Singh… - Microchemical …, 2024 - Elsevier
Environmental issues have raised serious concerns for human health, one of which is the
uncontrolled release of dangerous pollutants like toxic heavy metals ions (HMIs) from …

ICP-MS: analytical method for identification and detection of elemental impurities

M Mittal, K Kumar, D Anghore… - Current drug discovery …, 2017 - benthamdirect.com
Aim of this article is to review and discuss the currently used quantitative analytical method
ICP-MS, which is used for quality control of pharmaceutical products. ICP-MS technique has …

Development and validation of an ICP-OES method for quantitation of elemental impurities in tablets according to coming US pharmacopeia chapters

C Støving, H Jensen, B Gammelgaard… - Journal of pharmaceutical …, 2013 - Elsevier
Abstract May 1, 2014 the United States Pharmacopeia (USP) will implement two new
chapters stating limit concentrations of elemental impurities in pharmaceuticals applying …

An overview of sample preparation procedures for determination of elemental impurities in medicines

FC Pinheiro, JA Nobrega - Microchemical Journal, 2022 - Elsevier
Elemental impurities determination in pharmaceuticals has become an emerging topic in the
last years due to the revision of the Chapter 231 from the United States Pharmacopeia by …