In the last few years, the pyridazine derivatives have been found to exhibit a wide range of
pharmacological activities. A large number of research articles and patents described them …

In spite of the availability of a large number of anti-inflammatory and analgesic agents,
fighting pain and inflammation remains a common problem. The current review article …

Abstract Thiosemicarbazides (2a–e) were obtained by the interaction of pyridine-4-
carboxylic acid hydrazide (1) with five different isothiocyanate (RNCS) derivatives. By …

Pyridazinones are important nitrogen‐rich heterocyclic core that has been driving the
substantial medicinal interest due to their wide range of biological activities. This privileged …

Abstract Rhizomes of Curcuma phaeocaulis Valeton (Zingiberaceae) have traditionally been
used for controlling inflammatory conditions. Numerous studies have aimed to isolate and …

Abstract In this study, 12 new 3 (2 H)-pyridazinone derivatives carrying 4-substituted
phenylpiperazinylethyl moiety on lactam nitrogen were synthesized and their chemical …

Background Despite significant progresses in antimicrobial therapy, infectious diseases
caused by bacteria and fungi remain a major worldwide health problem because of the rapid …

The pyridazinone derivatives have diverse biological potential and are easily synthesized.
Due to this, researchers and chemists have paid attention to the design and development of …

There is increased focus on developed non-steroidal anti-inflammatory drugs (NSAIDs)
containing a pyridazine nucleus. The NSAIDs are one of the most commonly used …

This work establishes the 'click'nature of the base-catalyzed oxirane ring opening reaction
by the selenolate nucleophile. The 'click'-generated ß-hydroxy selenide can be alkylated to …