An understanding of how axons elongate is needed to develop rational strategies to treat
neurological diseases and nerve injury. Growth cone-mediated neuronal elongation is …

In mammals, mechanics at multiple stages—nucleus to cell to ECM—underlie multiple
physiological and pathological functions from its development to reproduction to death …

Stretchable synaptic transistors (SSTs) are of paramount importance for the development of
soft machines and neuromorphic systems. Unfortunately, the reports about SSTs are very …

Mechanical stimulation plays an important role in the development and remodeling of
tendons. Tendon-derived stem cells (TDSCs) are an attractive cell source for tendon injury …

External forces are increasingly recognized as major regulators of cellular structure and
function, yet the underlying mechanism by which cells sense forces and transduce them into …

The aim of cardiovascular regeneration is to mimic the biological and mechanical
functioning of tissues. For this it is crucial to recapitulate the in vivo cellular organization …

Stress fiber realignment is an important adaptive response to cyclic stretch for nonmuscle
cells, but the mechanism by which such reorganization occurs is not known. By analyzing …

Polydimethylsiloxane (PDMS) is a bioinert synthetic polymer with tunable elastic properties
that is commonly used as a cell culture substrate. Although plasma treatments are widely …

Effective intracellular transport of proteins and organelles is critical in cells and is especially
important for ensuring proper neuron functionality. In neurons, most proteins are synthesized …

We have developed an integrated strain array for cell culture enabling high-throughput
mechano-transduction studies. Biocompatible cell culture chambers were integrated with an …