The role of polyphenol (flavonoids) compounds in the treatment of cancer cells

A Hazafa, KU Rehman, N Jahan, Z Jabeen - Nutrition and cancer, 2020 - Taylor & Francis
Cancer remains a second leading cause of deaths and major public health problem. It
occurs due to extensive DNA damage caused by ultraviolet radiations, ionizing radiations …

The role of dietary phenolic compounds in protein digestion and processing technologies to improve their antinutritive properties

TD Cirkovic Velickovic… - … Reviews in Food …, 2018 - Wiley Online Library
Digestion is the key step for delivering nutrients and bioactive substances to the body. The
way different food components interact with each other and with digestive enzymes can …

Modifications of dietary flavonoids towards improved bioactivity: An update on structure–activity relationship

L Chen, H Teng, Z Xie, H Cao, WS Cheang… - Critical reviews in …, 2018 - Taylor & Francis
Over the past two decades, extensive studies have revealed that inflammation represents a
major risk factor for various human diseases. Chronic inflammatory responses predispose to …

Recovery, concentration and purification of phenolic compounds by adsorption: A review

ML Soto, A Moure, H Domínguez, JC Parajó - Journal of Food Engineering, 2011 - Elsevier
Processing of solutions containing phenolics by adsorption–desorption enables the
recovery and purification of bioactive compounds or fractions from plant. This work reviews …

Human cancer cell antiproliferative and antioxidant activities of Juglans regia L.

M Carvalho, PJ Ferreira, VS Mendes, R Silva… - Food and chemical …, 2010 - Elsevier
Several studies suggest that regular consumption of nuts, mostly walnuts, may have
beneficial effects against oxidative stress mediated diseases such as cardiovascular …

The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges

GR Tundo, D Sbardella, AM Santoro, A Coletta… - Pharmacology & …, 2020 - Elsevier
Abstract Ubiquitin Proteasome System (UPS) is an adaptable and finely tuned system that
sustains proteostasis network under a large variety of physiopathological conditions. Its …

Screening of crude plant extracts with anti-obesity activity

C Roh, U Jung - International Journal of Molecular Sciences, 2012 - mdpi.com
Obesity is a global health problem. It is also known to be a risk factor for the development of
metabolic disorders, type 2 diabetes, systemic hypertension, cardiovascular disease …

[HTML][HTML] Applications of Friedel–Crafts reactions in total synthesis of natural products

MM Heravi, V Zadsirjan, P Saedi, T Momeni - RSC advances, 2018 - pubs.rsc.org
Over the years, Friedel–Crafts (FC) reactions have been acknowledged as the most useful
and powerful synthetic tools for the construction of a special kind of carbon–carbon bond …

The role of natural polyphenols in cell signaling and cytoprotection against cancer development

H Lewandowska, M Kalinowska… - The Journal of nutritional …, 2016 - Elsevier
The cytoprotective and anticancer action of dietary in-taken natural polyphenols has for long
been attributed only to their direct radical scavenging activities. Currently it is well supported …

Anticancer properties of flavonoids: roles in various stages of carcinogenesis

N Clere, S Faure, M Carmen Martinez… - … Agents in Medicinal …, 2011 - ingentaconnect.com
High dietary intake of fruits and vegetables is consistently associated with a reduced risk of
common human cancers. The specific mechanisms of action of most phytochemicals in …