Estrogen synthesis and signaling pathways during aging: from periphery to brain

J Cui, Y Shen, R Li - Trends in molecular medicine, 2013 - cell.com
Estrogens are the primary female sex hormones and play important roles in both
reproductive and non-reproductive systems. Estrogens can be synthesized in non …

An overview on estrogen receptors signaling and its ligands in breast cancer

MZI Khan, M Uzair, A Nazli, JZ Chen - European Journal of Medicinal …, 2022 - Elsevier
Estrogen governs the regulations of various pathological and physiological actions
throughout the body in both males and females. Generally, 17β-estradiol an endogenous …

Estrogen: a master regulator of bioenergetic systems in the brain and body

JR Rettberg, J Yao, RD Brinton - Frontiers in neuroendocrinology, 2014 - Elsevier
Estrogen is a fundamental regulator of the metabolic system of the female brain and body.
Within the brain, estrogen regulates glucose transport, aerobic glycolysis, and mitochondrial …

Estrogen receptors in the central nervous system and their implication for dopamine-dependent cognition in females

A Almey, TA Milner, WG Brake - Hormones and behavior, 2015 - Elsevier
This article is part of a Special Issue “Estradiol and cognition”. Over the past 30 years,
research has demonstrated that estrogens not only are important for female reproduction …

Hormone-mediated neural remodeling orchestrates parenting onset during pregnancy

R Ammari, F Monaca, M Cao, E Nassar, P Wai… - Science, 2023 - science.org
During pregnancy, physiological adaptations prepare the female body for the challenges of
motherhood. Becoming a parent also requires behavioral adaptations. Such adaptations …

[HTML][HTML] The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis

MA Cowley, RG Smith, S Diano, M Tschöp, N Pronchuk… - Neuron, 2003 - cell.com
The gastrointestinal peptide hormone ghrelin stimulates appetite in rodents and humans via
hypothalamic actions. We discovered expression of ghrelin in a previously uncharacterized …

Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes

L Björnström, M Sjöberg - Molecular endocrinology, 2005 - academic.oup.com
Estrogen receptors (ERs) act by regulating transcriptional processes. The classical
mechanism of ER action involves estrogen binding to receptors in the nucleus, after which …

Estrogenic endocrine disruptors: Molecular mechanisms of action

R Kiyama, Y Wada-Kiyama - Environment International, 2015 - Elsevier
A comprehensive summary of more than 450 estrogenic chemicals including estrogenic
endocrine disruptors is provided here to understand the complex and profound impact of …

[HTML][HTML] Estrogen and its role in thyroid cancer

M Derwahl, D Nicula - Endocrine-related cancer, 2014 - erc.bioscientifica.com
Proliferative thyroid diseases are more prevalent in females than in males. Upon the onset of
puberty, the incidence of thyroid cancer increases in females only and declines again after …

Endocrine disrupters: a review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems

C Frye, E Bo, G Calamandrei, L Calza… - Journal of …, 2012 - Wiley Online Library
Some environmental contaminants interact with hormones and may exert adverse
consequences as a result of their actions as endocrine disrupting chemicals (EDCs) …