[HTML][HTML] Mast cells and their progenitors in allergic asthma
E Méndez-Enríquez, J Hallgren - Frontiers in immunology, 2019 - frontiersin.org
Mast cells and their mediators have been implicated in the pathogenesis of asthma and
allergy for decades. Allergic asthma is a complex chronic lung disease in which several …
allergy for decades. Allergic asthma is a complex chronic lung disease in which several …
[HTML][HTML] Mast cell progenitors: origin, development and migration to tissues
JS Dahlin, J Hallgren - Molecular immunology, 2015 - Elsevier
Mast cells in tissues are developed from mast cell progenitors emerging from the bone
marrow in a process highly regulated by transcription factors. Through the advancement of …
marrow in a process highly regulated by transcription factors. Through the advancement of …
Lin− CD34hi CD117int/hi FcεRI+ cells in human blood constitute a rare population of mast cell progenitors
JS Dahlin, A Malinovschi, H Öhrvik… - Blood, The Journal …, 2016 - ashpublications.org
Mast cells are rare tissue-resident immune cells that are involved in allergic reactions, and
their numbers are increased in the lungs of asthmatics. Murine lung mast cells arise from …
their numbers are increased in the lungs of asthmatics. Murine lung mast cells arise from …
Mast cell‐derived serotonin enhances methacholine‐induced airway hyperresponsiveness in house dust mite‐induced experimental asthma
E Mendez‐Enriquez, PA Alvarado‐Vazquez, W Abma… - Allergy, 2021 - Wiley Online Library
Background Airway hyperresponsiveness (AHR) is a feature of asthma in which airways are
hyperreactive to stimuli causing extensive airway narrowing. Methacholine provocations …
hyperreactive to stimuli causing extensive airway narrowing. Methacholine provocations …
[HTML][HTML] Interleukin-9 promotes mast cell progenitor proliferation and CCR2-dependent mast cell migration in allergic airway inflammation
A Pajulas, Y Fu, CCL Cheung, M Chu, A Cannon… - Mucosal …, 2023 - Elsevier
Allergic asthma is a chronic lung disease characterized by airway hyperresponsiveness and
cellular infiltration that is exacerbated by immunoglobulin E-dependent mast cell (MC) …
cellular infiltration that is exacerbated by immunoglobulin E-dependent mast cell (MC) …
The innate immune response in myocardial infarction, repair, and regeneration
R Gentek, G Hoeffel - The immunology of cardiovascular homeostasis and …, 2017 - Springer
Following myocardial infarction (MI), resident innate immune cells such as macrophages,
innate lymphoid cells, and mast cells rapidly coordinate their function to contain …
innate lymphoid cells, and mast cells rapidly coordinate their function to contain …
[HTML][HTML] Tolerogenic IDO+ Dendritic Cells Are Induced by PD-1-Expressing Mast Cells
Mast cells (MCs) are tissue resident cells, rich in inflammatory mediators, involved in allergic
reactions, and with an increasingly recognized role in immunomodulation. Dendritic cells …
reactions, and with an increasingly recognized role in immunomodulation. Dendritic cells …
Distinguishing mast cell progenitors from mature mast cells in mice
Mast cells originate from the bone marrow and develop into c-kit+ FcɛRI+ cells. Both mast
cell progenitors (MCp) and mature mast cells express these cell surface markers, and ways …
cell progenitors (MCp) and mature mast cells express these cell surface markers, and ways …
[HTML][HTML] Influenza infection in mice induces accumulation of lung mast cells through the recruitment and maturation of mast cell progenitors
B Zarnegar, E Mendez-Enriquez, A Westin… - Frontiers in …, 2017 - frontiersin.org
Mast cells (MCs) are powerful immune cells that mature in the peripheral tissues from bone
marrow (BM)-derived mast cell progenitors (MCp). Accumulation of MCs in lung …
marrow (BM)-derived mast cell progenitors (MCp). Accumulation of MCs in lung …
Circulating mast cell progenitors correlate with reduced lung function in allergic asthma
M Salomonsson, A Malinovschi… - Clinical & …, 2019 - Wiley Online Library
Background Studies using mouse models have revealed that mast cell progenitors are
recruited from the blood circulation to the lung during acute allergic airway inflammation …
recruited from the blood circulation to the lung during acute allergic airway inflammation …