Overlooking evolution: a systematic analysis of cancer relapse and therapeutic resistance research

CA Aktipis, VSY Kwan, KA Johnson, SL Neuberg… - PloS one, 2011 - journals.plos.org
Cancer therapy selects for cancer cells resistant to treatment, a process that is fundamentally
evolutionary. To what extent, however, is the evolutionary perspective employed in research …

Predictive values of pathological and clinical risk factors for positivity of sentinel lymph node biopsy in thin melanoma: a systematic review and meta-analysis

H Huang, Z Fu, J Ji, J Huang, X Long - Frontiers in Oncology, 2022 - frontiersin.org
Background The indications for sentinel lymph node biopsy (SLNB) for thin melanoma are
still unclear. This meta-analysis aims to determine the positive rate of SLNB in thin …

[HTML][HTML] NF‑κB inhibition is associated with OPN/MMP‑9 downregulation in cutaneous melanoma

C Guarneri, V Bevelacqua, J Polesel… - Oncology …, 2017 - spandidos-publications.com
The development of cutaneous melanoma is influenced by genetic factors, including BRAF
mutations and environmental factors, such as ultraviolet exposure. Its progression has been …

[HTML][HTML] Objective assessment of blood and lymphatic vessel invasion and association with macrophage infiltration in cutaneous melanoma

SJ Storr, S Safuan, A Mitra, F Elliott, C Walker… - Modern Pathology, 2012 - Elsevier
The aims of this study were to investigate the role of vascular invasion (blood and
lymphatic), vessel density and the presence of tumour-associated macrophages as …

Is head and neck melanoma different from trunk and extremity melanomas with respect to sentinel lymph node status and clinical outcome?

N Fadaki, R Li, B Parrett, G Sanders… - Annals of surgical …, 2013 - Springer
Background Previous studies showed conflicting and inconsistent results regarding the
effect of anatomic location of the melanoma on sentinel lymph node (SLN) positivity and/or …

[HTML][HTML] Sentinel node biopsy in patients with melanoma improves the accuracy of staging when added to clinicopathological features of the primary tumor

MA El Sharouni, MD Stodell, T Ahmed… - Annals of …, 2021 - Elsevier
Background It has been claimed, without supporting evidence, that knowledge of sentinel
node (SN) status does not provide more accurate prognostic information than basic …

Factors predictive of the status of sentinel lymph nodes in melanoma patients from a large multicenter database

RL White, GD Ayers, VH Stell, S Ding… - Annals of surgical …, 2011 - Springer
Background Numerous predictive factors for cutaneous melanoma metastases to sentinel
lymph nodes have been identified; however, few have been found to be reproducibly …

The neutrophil–lymphocyte ratio and locoregional melanoma: a multicentre cohort study

AV Robinson, C Keeble, MCI Lo, O Thornton… - Cancer Immunology …, 2020 - Springer
Objectives The neutrophil–lymphocyte ratio (NLR) is an inflammatory biomarker which is
useful in cancer prognostication. We aimed to investigate the differences in baseline NLR …

Tumor cell adhesion as a risk factor for sentinel lymph node metastasis in primary cutaneous melanoma

A Meves, E Nikolova, JB Heim… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Less than 20% of patients with melanoma who undergo sentinel lymph node (SLN)
biopsy based on American Society of Clinical Oncology/Society of Surgical Oncology …

No survival benefit for patients with melanoma undergoing sentinel lymph node biopsy: critical appraisal of the Multicenter Selective Lymphadenectomy Trial‐I final …

M Sladden, S Zagarella, C Popescu… - British Journal of …, 2015 - academic.oup.com
Background Sentinel lymph node biopsy (SLNB) was developed in the hope that it would
improve outcomes for patients with melanoma. SLNB is an area of discussion and …