D-Serine: potential therapeutic agent and/or biomarker in schizophrenia and depression?
MAB MacKay, M Kravtsenyuk, R Thomas… - Frontiers in …, 2019 - frontiersin.org
D-Serine is a potent co-agonist at the NMDA glutamate receptor and has been the object of
many preclinical studies to ascertain the nature of its metabolism, its regional and cellular …
many preclinical studies to ascertain the nature of its metabolism, its regional and cellular …
Strategies to enhance N-methyl-D-aspartate receptor-mediated neurotransmission in schizophrenia, a critical review and meta-analysis
GE Tsai, PY Lin - Current pharmaceutical design, 2010 - ingentaconnect.com
Although hypofunction of N-methyl-D-aspartate (NMDA) receptor-mediated
neurotransmission is proposed to play an important role in the pathophysiology of …
neurotransmission is proposed to play an important role in the pathophysiology of …
[图书][B] Handbook of vitamins
J Zempleni, JW Suttie, JF Gregory III, PJ Stover - 2013 - books.google.com
Within the last few years, knowledge about vitamins has increased dramatically. This new
edition of a bestseller presents comprehensive summaries that analyze the chemical …
edition of a bestseller presents comprehensive summaries that analyze the chemical …
Glutamatergic synaptic dysregulation in schizophrenia: therapeutic implications
Schizophrenia affects approximately 1% of the population and continues to be associated
with poor outcome because of the limited efficacy of and noncompliance with existing …
with poor outcome because of the limited efficacy of and noncompliance with existing …
Human D-amino acid oxidase: structure, function, and regulation
D-Amino acid oxidase (DAAO) is an FAD-containing flavoenzyme that catalyzes with
absolute stereoselectivity the oxidative deamination of all natural D-amino acids, the only …
absolute stereoselectivity the oxidative deamination of all natural D-amino acids, the only …
Glial D-Serine Gates NMDA Receptors at Excitatory Synapses in Prefrontal Cortex
N-methyl-d-aspartate receptors (NMDARs) subserve numerous neurophysiological and
neuropathological processes in the cerebral cortex. Their activation requires the binding of …
neuropathological processes in the cerebral cortex. Their activation requires the binding of …
The neurobiology of D-amino acid oxidase and its involvement in schizophrenia
L Verrall, PWJ Burnet, JF Betts, PJ Harrison - Molecular psychiatry, 2010 - nature.com
D-amino acid oxidase (DAO) is a flavoenzyme that metabolizes certain D-amino acids,
notably the endogenous N-methyl D-aspartate receptor (NMDAR) co-agonist, D-serine. As …
notably the endogenous N-methyl D-aspartate receptor (NMDAR) co-agonist, D-serine. As …
Grading the commercial optical biosensor literature—Class of 2008:'The Mighty Binders'
RL Rich, DG Myszka - Journal of Molecular Recognition: An …, 2010 - Wiley Online Library
Optical biosensor technology continues to be the method of choice for label‐free, real‐time
interaction analysis. But when it comes to improving the quality of the biosensor literature …
interaction analysis. But when it comes to improving the quality of the biosensor literature …
Genetic association studies of glutamate, GABA and related genes in schizophrenia and bipolar disorder: a decade of advance
SYT Cherlyn, P San Woon, JJ Liu, WY Ong… - Neuroscience & …, 2010 - Elsevier
Schizophrenia (SZ) and bipolar disorder (BD) are debilitating neurobehavioural disorders
likely influenced by genetic and non-genetic factors and which can be seen as complex …
likely influenced by genetic and non-genetic factors and which can be seen as complex …
Analysis of free D-serine in mammals and its biological relevance
T Nishikawa - Journal of Chromatography B, 2011 - Elsevier
d-Serine is a unique endogenous substance enriched in the brain at the exceptionally high
concentrations as a free d-amino acid in mammals throughout their life. Peripheral tissues …
concentrations as a free d-amino acid in mammals throughout their life. Peripheral tissues …