Immunometabolism in early and late stages of rheumatoid arthritis
CM Weyand, JJ Goronzy - Nature Reviews Rheumatology, 2017 - nature.com
One of the fundamental traits of immune cells in rheumatoid arthritis (RA) is their ability to
proliferate, a property shared with the joint-resident cells that form the synovial pannus. The …
proliferate, a property shared with the joint-resident cells that form the synovial pannus. The …
[HTML][HTML] Metabolomics for the masses: The future of metabolomics in a personalized world
Current clinical practices focus on a small number of biochemical directly related to the
pathophysiology with patients and thus only describe a very limited metabolome of a patient …
pathophysiology with patients and thus only describe a very limited metabolome of a patient …
Cachexia induced by cancer and chemotherapy yield distinct perturbations to energy metabolism
Background Cancer cachexia is a metabolic disorder involving perturbed energy balance
and altered mitochondrial function. Chemotherapy is a primary treatment option for many …
and altered mitochondrial function. Chemotherapy is a primary treatment option for many …
GlycA: a composite nuclear magnetic resonance biomarker of systemic inflammation
JD Otvos, I Shalaurova, J Wolak-Dinsmore… - Clinical …, 2015 - academic.oup.com
BACKGROUND Nuclear magnetic resonance (NMR) spectra of serum obtained under
quantitative conditions for lipoprotein particle analyses contain additional signals that could …
quantitative conditions for lipoprotein particle analyses contain additional signals that could …
The biomarker GlycA is associated with chronic inflammation and predicts long-term risk of severe infection
The biomarker glycoprotein acetylation (GlycA) has been shown to predict risk of
cardiovascular disease and all-cause mortality. Here, we characterize biological processes …
cardiovascular disease and all-cause mortality. Here, we characterize biological processes …
Metabolomics in rheumatoid arthritis: Advances and review
L Xu, C Chang, P Jiang, K Wei, R Zhang, Y Jin… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease accompanied by metabolic alterations.
The metabolic profiles of patients with RA can be determined using targeted and non …
The metabolic profiles of patients with RA can be determined using targeted and non …
Functional analysis of colonic bacterial metabolism: relevant to health?
HM Hamer, V De Preter, K Windey… - American Journal of …, 2012 - journals.physiology.org
With the use of molecular techniques, numerous studies have evaluated the composition of
the intestinal microbiota in health and disease. However, it is of major interest to supplement …
the intestinal microbiota in health and disease. However, it is of major interest to supplement …
Differences in the serum metabolome and lipidome identify potential biomarkers for seronegative rheumatoid arthritis versus psoriatic arthritis
M Souto-Carneiro, L Tóth, R Behnisch… - Annals of the …, 2020 - ard.bmj.com
Objectives The differential diagnosis of seronegative rheumatoid arthritis (negRA) and
psoriasis arthritis (PsA) is often difficult due to the similarity of symptoms and the …
psoriasis arthritis (PsA) is often difficult due to the similarity of symptoms and the …
Global metabolite profiling of synovial fluid for the specific diagnosis of rheumatoid arthritis from other inflammatory arthritis
Currently, reliable biomarkers that can be used to distinguish rheumatoid arthritis (RA) from
other inflammatory diseases are unavailable. To find possible distinctive metabolic patterns …
other inflammatory diseases are unavailable. To find possible distinctive metabolic patterns …
The impact of inflammation on metabolomic profiles in patients with arthritis
Objective Inflammatory arthritis is associated with systemic manifestations including
alterations in metabolism. We used nuclear magnetic resonance (NMR) spectroscopy …
alterations in metabolism. We used nuclear magnetic resonance (NMR) spectroscopy …