Converting nanotoxicity data to information using artificial intelligence and simulation
Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …
However, data is not equal to information. The question is how to extract critical information …
Advances in drug delivery systems utilizing blood cells and their membrane-derived microvesicles
A He, Y Huang, C Cao, X Li - Drug Delivery, 2024 - Taylor & Francis
The advancement of drug delivery systems (DDSs) in recent decades has demonstrated
significant potential in enhancing the efficacy of pharmacological agents. Despite the …
significant potential in enhancing the efficacy of pharmacological agents. Despite the …
Thermal-controlled cellular uptake of “hot” nanoparticles
Nanoparticles (NPs) have shown immense potential in the field of biomedical applications,
particularly in NP-based photothermal therapy, which offers a remote-controlled approach to …
particularly in NP-based photothermal therapy, which offers a remote-controlled approach to …
Synergistic entry of individual nanoparticles into mammalian cells driven by free energy decline and regulated by their sizes
Cell entry is one of the common prerequisites for nanomaterial applications. Despite
extensive studies on a homogeneous group of nanoparticles (NPs), fewer studies have …
extensive studies on a homogeneous group of nanoparticles (NPs), fewer studies have …
Non-equilibrium transport of nanoparticles across the lipid membrane
Development of effective strategies for the internalization of nanoparticles is essential in
many applications, such as drug delivery. Most, if not all, previous studies are based on …
many applications, such as drug delivery. Most, if not all, previous studies are based on …
Membrane-curvature-mediated co-endocytosis of bystander and functional nanoparticles
Efficient cellular uptake of nanoparticles (NPs) is necessary for the development of
nanomedicine in biomedical applications. Recently, the coadministration of functionalized …
nanomedicine in biomedical applications. Recently, the coadministration of functionalized …
Computational study on the regulatory mechanism of cell membrane wrapping on liposomes by embedded bowl-like nanostructures for drug delivery
R Kang, S Li, Y Li, X Zhang, T Yue - ACS Applied Nano Materials, 2022 - ACS Publications
Controlling the nanoparticle's (NP) ability to facilitate cell uptake is particularly desirable for
biomedical applications, such as drug delivery. Despite growing evidence highlighting the …
biomedical applications, such as drug delivery. Despite growing evidence highlighting the …
Molecular insights into the resistance of phospholipid heads to the membrane penetration of graphene nanosheets
The interaction between nanomaterials and phospholipid membranes underlies many
emerging biological applications. To what extent hydrophilic phospholipid heads shield the …
emerging biological applications. To what extent hydrophilic phospholipid heads shield the …
Association mechanism of peptide-coated metal nanoparticles with model membranes: A coarse-grained study
Functionalized metal nanoparticles (NPs) hold great promise as innovative tools in
nanomedicine. However, one of the main challenges is how to optimize their association …
nanomedicine. However, one of the main challenges is how to optimize their association …
Endocytosis efficiency and targeting ability by the cooperation of nanoparticles
T Ma, T Chen, H Tan, S Zhang, H Wei, Q Wang… - Nanoscale, 2024 - pubs.rsc.org
Cooperative wrapping of nanoparticles (NPs) with small sizes is an important pathway for
the uptake of NPs by cell membranes. However, the cooperative wrapping efficiency and the …
the uptake of NPs by cell membranes. However, the cooperative wrapping efficiency and the …