ATP-dependent chromatin remodeling during mammalian development
SK Hota, BG Bruneau - Development, 2016 - journals.biologists.com
Precise gene expression ensures proper stem and progenitor cell differentiation, lineage
commitment and organogenesis during mammalian development. ATP-dependent …
commitment and organogenesis during mammalian development. ATP-dependent …
The BAF complex in development and disease
A Alfert, N Moreno, K Kerl - Epigenetics & chromatin, 2019 - Springer
The ATP-dependent chromatin remodelling complex BAF (= mammalian SWI/SNF complex)
is crucial for the regulation of gene expression and differentiation. In the course of evolution …
is crucial for the regulation of gene expression and differentiation. In the course of evolution …
The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells
Pioneer transcription factors recognise and bind their target sequences in inaccessible
chromatin to establish new transcriptional networks throughout development and cellular …
chromatin to establish new transcriptional networks throughout development and cellular …
A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells
The role of individual subunits in the targeting and function of the mammalian BRG1-
associated factors (BAF) complex in embryonic stem cell (ESC) pluripotency maintenance …
associated factors (BAF) complex in embryonic stem cell (ESC) pluripotency maintenance …
Chromatin remodeling and bivalent histone modifications in embryonic stem cells
A Harikumar, E Meshorer - EMBO reports, 2015 - embopress.org
Pluripotent embryonic stem cells (ESC s) are characterized by distinct epigenetic features
including a relative enrichment of histone modifications related to active chromatin. Among …
including a relative enrichment of histone modifications related to active chromatin. Among …
[HTML][HTML] Global identification of SWI/SNF targets reveals compensation by EP400
BJE Martin, EF Ablondi, C Goglia, CA Mimoso… - Cell, 2023 - cell.com
Mammalian SWI/SNF chromatin remodeling complexes move and evict nucleosomes at
gene promoters and enhancers to modulate DNA access. Although SWI/SNF subunits are …
gene promoters and enhancers to modulate DNA access. Although SWI/SNF subunits are …
MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells
The polybromo-associated PBAF (SWI/SNF) chromatin remodeling complex, which includes
PBRM1, ARID2, and BRD7, regulates cell differentiation and genomic integrity. MUC1-C is …
PBRM1, ARID2, and BRD7, regulates cell differentiation and genomic integrity. MUC1-C is …
Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation
N Roy, S Malik, KE Villanueva, A Urano… - Genes & …, 2015 - genesdev.cshlp.org
Pancreatic ductal adenocarcinoma (PDA) develops predominantly through pancreatic
intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasm (IPMN) …
intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasm (IPMN) …
MUC1-C activates the BAF (mSWI/SNF) complex in prostate cancer stem cells
M Hagiwara, Y Yasumizu, N Yamashita, H Rajabi… - Cancer research, 2021 - AACR
Abstract The Brg/Brahma-associated factor (BAF, mSWI/SNF) chromatin remodeling
complex is of importance in development and has been linked to prostate oncogenesis. The …
complex is of importance in development and has been linked to prostate oncogenesis. The …
Genome-wide transcriptional regulation mediated by biochemically distinct SWI/SNF complexes
Multiple positions within the SWI/SNF chromatin remodeling complex can be filled by
mutually exclusive subunits. Inclusion or exclusion of these proteins defines many unique …
mutually exclusive subunits. Inclusion or exclusion of these proteins defines many unique …