The clinical utility of anti-double-stranded DNA antibodies and the challenges of their determination

E Mummert, MJ Fritzler, C Sjöwall, C Bentow… - Journal of …, 2018 - Elsevier
Autoantibodies against double-stranded DNA (dsDNA) were first described> 60 years ago
and although they are still one of the most clinically relevant autoantibodies, test results may …

Anti-dsDNA testing specificity for systemic lupus erythematosus: a systematic review

ME Orme, A Voreck, R Aksouh… - The Journal of Applied …, 2022 - academic.oup.com
Background Autoantibody specificity in autoimmune diseases is variable due to each
patient's individual spectrum of autoantibodies and the inherent differences between …

Effectiveness and safety of belimumab in Chinese lupus patients: a multicenter, real-world observational study

F Sun, H Wu, Z Wang, T Wu, X Wu, J Chen, D Zhang… - Biomedicines, 2023 - mdpi.com
Objective: The effectiveness and safety of belimumab in Chinese lupus patients with
different disease activities were investigated in a real-world setting. Method: Patients who …

Comparison of current methods for anti‐dsDNA antibody detection and reshaping diagnostic strategies

M Infantino, B Palterer, G Previtali… - Scandinavian …, 2022 - Wiley Online Library
Anti–double‐stranded DNA antibodies (anti‐dsDNA) are considered a specific marker for
systemic lupus erythematosus (SLE). Though the Farr technique was once the reference …

Laboratory evaluation of anti-dsDNA antibodies

M Cockx, L Van Hoovels, E De Langhe, J Lenaerts… - Clinica Chimica …, 2022 - Elsevier
Antibodies to dsDNA are an important laboratory parameter for diagnosis, monitoring and
classification of systemic lupus erythematosus (SLE). In clinical laboratories, several …

Comparative analysis of contemporary anti-double stranded DNA antibody assays for systemic lupus erythematosus

CJ Bauer, P Karakostas, N Weber, C Behning… - Frontiers in …, 2023 - frontiersin.org
Objective Elevated double-stranded DNA (dsDNA) antibody levels in blood serum are
considered a disease-specific marker in systemic lupus erythematosus (SLE), correlate with …

Clinical evaluation of total and high-avidity anti-dsDNA antibody assays for the diagnosis of systemic lupus erythematosus

W Yuan, H Cao, P Wan, R Shi, S Zhou, J Zheng - Lupus, 2019 - journals.sagepub.com
Background This study evaluated the diagnostic performances of total and high-avidity (HA)
anti-dsDNA enzyme immunoassays (EIA) in Chinese systemic lupus erythematosus (SLE) …

Comparison study of bead-based and line-blot multiplex ANA immunoassays in the diagnosis of systemic autoimmune rheumatic diseases

W Yuan, H Cao, W Li, X Wu, J Zheng - Clinical Rheumatology, 2022 - Springer
Objectives Detection of antinuclear antibodies (ANA) by immunofluorescence assay (IFA) is
increasingly substituted by multiplex bead-based immunoassay (MBA) and line-blot …

Detection of epitopes in systemic lupus erythematosus using peptide microarray

X Li, H Li, Q Hu, J Lin, Q Zhang… - Molecular …, 2018 - spandidos-publications.com
Systemic lupus erythematosus (SLE) is a common autoimmune disease, which features the
secretion of antibodies directed against autoantigens in vivo. In the present study, a peptide …

Fully automated chemiluminescence microarray immunoassay for detection of antinuclear antibodies in systemic autoimmune rheumatic diseases

D Yuan, X Yang, C Ji, G Sun, Y Xu, Y Cao… - Journal of Laboratory …, 2024 - degruyter.com
Objectives Detection of specific antinuclear antibodies is very important in term of diagnosis,
prognosis and management of patients with systemic autoimmune rheumatic diseases …