Endothelial dysfunction, inflammation and coronary artery disease: potential biomarkers and promising therapeutical approaches
DJ Medina-Leyte, O Zepeda-García… - International journal of …, 2021 - mdpi.com
Coronary artery disease (CAD) and its complications are the leading cause of death
worldwide. Inflammatory activation and dysfunction of the endothelium are key events in the …
worldwide. Inflammatory activation and dysfunction of the endothelium are key events in the …
Dietary flavonoids: Cardioprotective potential with antioxidant effects and their pharmacokinetic, toxicological and therapeutic concerns
Flavonoids comprise a large group of structurally diverse polyphenolic compounds of plant
origin and are abundantly found in human diet such as fruits, vegetables, grains, tea, dairy …
origin and are abundantly found in human diet such as fruits, vegetables, grains, tea, dairy …
Oxidative stress-induced endothelial dysfunction in cardiovascular diseases
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better
understanding of the mechanisms underlying CVD is key for better management or …
understanding of the mechanisms underlying CVD is key for better management or …
Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and …
D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …
Thiazole ring—A biologically active scaffold
A Petrou, M Fesatidou, A Geronikaki - Molecules, 2021 - mdpi.com
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …
applications. Its derivatives have a wide range of biological activities such as antioxidant …
LRG1: an emerging player in disease pathogenesis
The secreted glycoprotein leucine-rich α-2 glycoprotein 1 (LRG1) was first described as a
key player in pathogenic ocular neovascularization almost a decade ago. Since then, an …
key player in pathogenic ocular neovascularization almost a decade ago. Since then, an …
Lycopene in the prevention of cardiovascular diseases
S Przybylska, G Tokarczyk - International Journal of Molecular Sciences, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of human mortality worldwide.
Oxidative stress and inflammation are pathophysiological processes involved in the …
Oxidative stress and inflammation are pathophysiological processes involved in the …
[HTML][HTML] The role of nutrition in COVID-19 susceptibility and severity of disease: a systematic review
Background Many nutrients have powerful immunomodulatory actions with the potential to
alter susceptibility to coronavirus disease 2019 (COVID-19) infection, progression to …
alter susceptibility to coronavirus disease 2019 (COVID-19) infection, progression to …
The effect of dietary polyphenols on vascular health and hypertension: current evidence and mechanisms of action
The aim of this review was to explore existing evidence from studies conducted on humans
and summarize the mechanisms of action of dietary polyphenols on vascular health, blood …
and summarize the mechanisms of action of dietary polyphenols on vascular health, blood …
Oxidative stress status in COVID-19 patients hospitalized in intensive care unit for severe pneumonia. A pilot study
J Pincemail, E Cavalier, C Charlier, JP Cheramy–Bien… - Antioxidants, 2021 - mdpi.com
Background: A key role of oxidative stress has been highlighted in the pathogenesis of
COVID-19. However, little has been said about oxidative stress status (OSS) of COVID-19 …
COVID-19. However, little has been said about oxidative stress status (OSS) of COVID-19 …