IL‐37 is a unique member of the IL‐1 family of cytokines, which functions as a natural
suppressor of inflammatory and immune responses. Immune and non‐immune cells …

The role of the cytokines and receptors of the IL-1 family in inflammation is well known.
Several cytokines of the family have a powerful inflammatory activity, with IL-1β being the …

IL‐37 is unique in the IL‐1 family in that unlike other members of the family, IL‐37 broadly
suppresses innate immunity. IL‐37 can be elevated in humans with inflammatory and …

Inflammasomes are supramolecular platforms that organize in response to various damage-
associated molecular patterns and pathogen-associated molecular patterns. Upon …

Chronic kidney disease (CKD) is inherently an inflammatory condition, which ultimately
results in the development of end stage renal disease or cardiovascular events. Low-grade …

In recent years, the landscape of pro-and anti-inflammatory cytokines has rapidly expanded
with the identification of new members proven to be involved at different extent in the …

Autoimmune/inflammatory diseases affect many people and are an important cause of
global incidence and mortality. Mesenchymal stem cells (MSCs) have low immunogenicity …

IL-37, a new member of the IL-1 cytokine family, is a natural inhibitor of innate immunity
associated with autoimmune diseases. This study was undertaken to evaluate whether IL-37 …

Background The aim of this study was to assess interleukin (IL)-37 production in asthmatic
children in serum and induced sputum and to look to the impact of IL-37 on pro-inflammatory …

Inflammatory bowel diseases (IBD) include ulcerative colitis and Crohn's disease. The
immune response in ulcerative colitis is different from the Crohn's disease. Accumulating …