Hyperpolarized (HP) carbon 13 (13C) MRI is an emerging molecular imaging method that
allows rapid, noninvasive, and pathway-specific investigation of dynamic metabolic and …

Clinical medicine has experienced a rapid development in recent decades, during which
therapies targeting specific cellular signaling pathways, or specific cell surface receptors …

Purpose To ameliorate tradeoffs between a fixed spatial resolution and signal‐to‐noise ratio
(SNR) for hyperpolarized 13C MRI. Methods In MRI, SNR is proportional to voxel volume but …

Kinetic modeling of the in vivo pyruvate-to-lactate conversion is crucial to investigating
aberrant cancer metabolism that demonstrates Warburg effect modifications. Non-invasive …

The detection of alcohols by magnetic resonance techniques is important for their
characterization and the monitoring of chemical change. Hyperpolarization processes can …

Background In recent years, the ability of conventional magnetic resonance imaging (MRI),
including T1 contrast-enhanced (CE) MRI, to monitor high-efficacy therapies and predict …

Parahydrogen‐based nuclear spin hyperpolarization allows various magnetic‐resonance
applications, and it is particularly attractive because of its technical simplicity, low cost, and …

Purpose To investigate the correlation between renal ischemia and 13C‐urea T2 relaxation
rate in an acute kidney injury (AKI) rat model. Methods Six rats subjected to unilateral renal …

Magnetic resonance spectroscopy (MRS) is a non-invasive and non-ionizing technique,
enabling in vivo investigation of cardiac metabolism in normal and diseased hearts. In vivo …

Reports on gadolinium deposits in the body and brains of adults and children who
underwent contrast-enhanced MRI examinations warrant development of new, metal free …