The chemokine ligand CCL2 and its receptor CCR2 are implicated in the initiation and
progression of various cancers. CCL2 can activate tumour cell growth and proliferation …

MMP-2 and MMP-9 genes have been suggested to play a role in breast cancer. Their
functions have been associated with invasion and metastasis of breast cancer; however …

Cell surface proteoglycans are known to be important regulators of many aspects of cell
behavior. The principal family of transmembrane proteoglycans is the syndecans, of which …

Simple Summary Despite the advancements in systemic treatments, the incidence of brain
metastasis (BM) is increasing. BM is a multi-step cascade. One critical event in BM is the …

Reactive oxygen species (ROS) are highly reactive oxygen-containing chemical species
formed as a by-product of normal aerobic respiration and also from a number of other …

The pathogenesis of many serious diseases, including cancer, is closely related to
disturbances in the angiogenesis process. Angiogenesis is essential for the progression of …

Background Colorectal cancer (CRC) is the third most common malignant tumor.
Fusobacterium nucleatum (F. nucleatum) is overabundant in CRC and associated with …

Triple-Negative Breast Cancer (TNBC) is a particularly aggressive subtype among breast
cancers (BCs), characterized by anoikis resistance, high invasiveness, and metastatic …

Oxidative stress is the leading cause of skin aging damage. Excessive accumulation of
reactive oxygen species (ROS) in cells induced by hydrogen peroxide (H2O2) triggers a …

Simple Summary Pancreatic cancer is difficult to treat. Novel treatment strategies are
urgently needed to improve the survival rate, which is approximately 10% five years after …