Malaria, which is caused by infection of red blood cells with Plasmodium parasites, can be
fatal in non-immune individuals if left untreated. The recent approval of the pre-erythrocytic …

Increasing levels of artemisinin and partner drug resistance threaten malaria control and
elimination globally. Triple artemisinin-based combination therapies (TACTs) which …

Artemisinin partial resistance (ART-R) in Plasmodium falciparum is one of the most pressing
threats to global malaria control. Over the last two decades, ART-R has spread widely …

As some previously reported studies have proven that amodiaquine, in addition to its
primary antimalarial activity, also has potential for new applications such as the inhibition of …

Historically Plasmodium falciparum has followed a pattern of drug resistance first appearing
in low transmission settings before spreading to high transmission settings. Several features …

When multiple beneficial alleles are present in a population but not linked together in any
one individual, there is no general evolutionary result that determines whether …