Genetic engineering of algae for enhanced biofuel production

R Radakovits, RE Jinkerson, A Darzins… - Eukaryotic …, 2010 - Am Soc Microbiol
There are currently intensive global research efforts aimed at increasing and modifying the
accumulation of lipids, alcohols, hydrocarbons, polysaccharides, and other energy storage …

ABC efflux pump-based resistance to chemotherapy drugs

PDW Eckford, FJ Sharom - Chemical reviews, 2009 - ACS Publications
Over 1 million new cases of all types of cancer are diagnosed each year in the United States
alone, and 559 650 cancer-related deaths were expected to occur in 2007. 1 …

Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system

B Sarkadi, L Homolya, G Szakács… - Physiological …, 2006 - journals.physiology.org
In this review we give an overview of the physiological functions of a group of ATP binding
cassette (ABC) transporter proteins, which were discovered, and still referred to, as …

The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME–Tox)

G Szakács, A Váradi, C Özvegy-Laczka, B Sarkadi - Drug discovery today, 2008 - Elsevier
ATP binding cassette (ABC) drug transporters play an important role in cancer drug
resistance, protection against xenobiotics, and in general in the passage of drugs through …

[HTML][HTML] Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression

T Nakanishi, DD Ross - Chinese journal of cancer, 2012 - ncbi.nlm.nih.gov
Breast cancer resistance protein (BCRP)/ATP-binding cassette subfamily G member 2
(ABCG2) is an ATP-binding cassette (ABC) transporter identified as a molecular cause of …

Plant ATP-binding cassette transporters

PA Rea - Annu. Rev. Plant Biol., 2007 - annualreviews.org
The ATP-binding cassette (ABC) protein superfamily is one of the largest known, with over
120 members in both Arabidopsis thaliana and rice (Oryza sativa). Most, but not all, ABC …

[HTML][HTML] ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer

F Quazi, S Lenevich, RS Molday - Nature communications, 2012 - nature.com
ATP-binding cassette (ABC) transporters comprise a superfamily of proteins, which actively
transport a variety of compounds across cell membranes. Mammalian and most eukaryotic …

Role of the breast cancer resistance protein (ABCG2) in drug transport

Q Mao - The AAPS journal, 2005 - Springer
The 72-kDa breast cancer resistance protein (BCRP) is the second member of the subfamily
G of the human ATP binding cassette (ABC) transporter superfamily and thus also …

[HTML][HTML] Diverse relations between ABC transporters and lipids: An overview

J Neumann, D Rose-Sperling, UA Hellmich - Biochimica et Biophysica Acta …, 2017 - Elsevier
It was first discovered in 1992 that P-glycoprotein (Pgp, ABCB1), an ATP binding cassette
(ABC) transporter, can transport phospholipids such as phosphatidylcholine,− ethanolamine …

Role of ABCG2/BCRP in biology and medicine

P Krishnamurthy, JD Schuetz - Annu. Rev. Pharmacol. Toxicol., 2006 - annualreviews.org
▪ Abstract The protein variously named ABCG2/BCRP/MXR/ABCP is a recently described
ATP-binding cassette (ABC) transporter originally identified by its ability to confer drug …