Abstract G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that
form within guanine-rich strands of regulatory genomic regions. G4s have been extensively …

Aromaticity is one of the most widely applied concepts within chemistry. It plays a major role
in the rationalization of a range of chemical properties in the electronic ground state, despite …

Since the beginning of scientific chemistry, chemists have been interested in light as an
energy source to induce chemical reactions. 1 Absorbing light, molecules reach an …

Since its first observation in 1907, ortho-quinone methide (o-QM) has occupied a strategic
place within the framework of reactive intermediates in organic synthesis. In recent years, o …

The major concern for anticancer chemotherapeutic agents is the host toxicity. The
development of anticancer prodrugs targeting the unique biochemical alterations in cancer …

The antiaromatic character of benzene in its first ππ* excited triplet state (T1) was deduced
more than four decades ago by Baird using perturbation molecular orbital (PMO) theory [J …

Electronic perturbation of quinone methides (QM) greatly influences their stability and in turn
alters the kinetics and product profile of QM reaction with deoxynucleosides. Consistent with …

The combination of neutral non-aromatic and zwitterionic aromatic contributing valence
bond structures confers a distinctive chemical reactivity to quinone methides, which has …

We have developed novel G-quadruplex (G-4) ligand/alkylating hybrid structures, tethering
the naphthalene diimide moiety to quaternary ammonium salts of Mannich bases, as …

Graphene oxide (GO), as a metal-free and readily available carbocatalyst, has been
extensively applied in catalytic organic transformations. This minireview aims to give an …