In situ motions of individual inner-hair-cell stereocilia from stapes stimulation in adult mice

Y Wang, CR Steele, S Puria, AJ Ricci - Communications biology, 2021 - nature.com
In vertebrate hearing organs, mechanical vibrations are converted to ionic currents through
mechanoelectrical-transduction (MET) channels. Concerted stereocilia motion produces an …

Fluid jet stimulation of auditory hair bundles reveal spatial non-uniformities and two viscoelastic-like mechanisms

AW Peng, AL Scharr, GA Caprara, D Nettles… - Frontiers in Cell and …, 2021 - frontiersin.org
Hair cell mechanosensitivity resides in the sensory hair bundle, an apical protrusion of actin-
filled stereocilia arranged in a staircase pattern. Hair bundle deflection activates mechano …

Coupling between the stereocilia of rat sensory inner-hair-cell hair bundles is weak, shaping their sensitivity to stimulation

AL Scharr, DÓ Maoiléidigh, AJ Ricci - Journal of Neuroscience, 2023 - Soc Neuroscience
The hair bundle is the universal mechanosensory organelle of auditory, vestibular, and
lateral-line systems. A bundle comprises mechanically coupled stereocilia, whose …