Abstract N6-methyladenosine (m6A) modification is the most prevalent internal mRNA
modification and is involved in many biological processes in eukaryotes. Accumulating …

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal type of cancer and the third
leading cause of cancer death with the lowest 5-year survival rate. Heterogeneity, difficulty in …

Pancreatic cancer is a malignancy with high mortality. In addition to the few symptoms until
the disease reaches an advanced stage, the high fatality rate is attributed to its rapid …

Background Triple-negative breast cancer (TNBC) is highly metastatic and lethal. Due to a
lack of druggable targets for this disease, there are no effective therapies in the clinic …

Objectives MicroRNAs are abundant in eukaryotic cells and play key roles in cancers.
Circular RNAs (CircRNAs) served as the competing endogenous RNAs (ceRNAs) in …

Cyclophilin A (CypA, also known as PPIA) is an essential member of the immunophilin
family. As an intracellular target of the immunosuppressive drug cyclosporin A (CsA) or a …

Purpose E-cadherin is a calcium-dependent glycoprotein whose main role is cell–cell
adhesion. Its transcriptional repressor TWIST1 is a basic helix–loop–helix (bHLH) protein …

Objective Oral squamous cell carcinoma (OSCC) is one of the most common cancers,
accounting for over 90% of malignant lesions in the oral cavity. Long non-coding RNAs play …

Background Without targets, triple negative breast cancer (TNBC) has the worst prognosis in
all subtypes of breast cancer (BC). Recently, eukaryotic translation initiation factor 3 m …

Gliomas are the most frequent tumors of the central nervous system (CNS) and include the
highly malignant glioblastoma (GBM). Characteristically, gliomas have translational control …