Astrocyte calcium signaling: the third wave
N Bazargani, D Attwell - Nature neuroscience, 2016 - nature.com
The discovery that transient elevations of calcium concentration occur in astrocytes, and
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
Gliotransmitters travel in time and space
The identification of the presence of active signaling between astrocytes and neurons in a
process termed gliotransmission has caused a paradigm shift in our thinking about brain …
process termed gliotransmission has caused a paradigm shift in our thinking about brain …
Three-dimensional Ca2+ imaging advances understanding of astrocyte biology
INTRODUCTION Astrocytes translate incoming information and generate functional outputs
via Ca2+ signaling. Thereby, they respond to neuronal activity, producing downstream …
via Ca2+ signaling. Thereby, they respond to neuronal activity, producing downstream …
Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles
A Mishra, JP Reynolds, Y Chen, AV Gourine… - Nature …, 2016 - nature.com
Active neurons increase their energy supply by dilating nearby arterioles and capillaries.
This neurovascular coupling underlies blood oxygen level–dependent functional imaging …
This neurovascular coupling underlies blood oxygen level–dependent functional imaging …
Coupling mechanism and significance of the BOLD signal: a status report
EMC Hillman - Annual review of neuroscience, 2014 - annualreviews.org
Functional magnetic resonance imaging (fMRI) provides a unique view of the working
human mind. The blood-oxygen-level-dependent (BOLD) signal, detected in fMRI, reflects …
human mind. The blood-oxygen-level-dependent (BOLD) signal, detected in fMRI, reflects …
Glial and neuronal control of brain blood flow
Blood flow in the brain is regulated by neurons and astrocytes. Knowledge of how these
cells control blood flow is crucial for understanding how neural computation is powered, for …
cells control blood flow is crucial for understanding how neural computation is powered, for …
Glia as sculptors of synaptic plasticity
L Sancho, M Contreras, NJ Allen - Neuroscience Research, 2021 - Elsevier
Glial cells are non-neuronal cells in the nervous system that are crucial for proper brain
development and function. Three major classes of glia in the central nervous system (CNS) …
development and function. Three major classes of glia in the central nervous system (CNS) …
Astrocyte regulation of blood flow in the brain
BA MacVicar, EA Newman - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Neuronal activity results in increased blood flow in the brain, a response named functional
hyperemia. Astrocytes play an important role in mediating this response. Neurotransmitters …
hyperemia. Astrocytes play an important role in mediating this response. Neurotransmitters …
Adult neurogenesis, glia, and the extracellular matrix
EC Cope, E Gould - Cell Stem Cell, 2019 - cell.com
In the adult mammalian hippocampus, new neurons arise from stem and progenitor cell
division, in a process known as adult neurogenesis. Adult-generated neurons are sensitive …
division, in a process known as adult neurogenesis. Adult-generated neurons are sensitive …
Cortical circuit activity evokes rapid astrocyte calcium signals on a similar timescale to neurons
Sensory stimulation evokes intracellular calcium signals in astrocytes; however, the timing of
these signals is disputed. Here, we used novel combinations of genetically encoded calcium …
these signals is disputed. Here, we used novel combinations of genetically encoded calcium …