Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities

X Jiang, K Wu, R Bai, P Zhang, Y Zhang - European Journal of Medicinal …, 2022 - Elsevier
Quinoxalinones are a class of heterocyclic compounds which attract extensive attention
owing to their potential in the field of organic synthesis and medicinal chemistry. During the …

Small-molecule inhibitors as potential therapeutics and as tools to understand the role of phospholipases A2

A Nikolaou, MG Kokotou, S Vasilakaki… - Biochimica et Biophysica …, 2019 - Elsevier
Abstract Phospholipase A 2 (PLA 2) enzymes are involved in various inflammatory
pathological conditions including arthritis, cardiovascular and autoimmune diseases. The …

[图书][B] Studies in natural products chemistry

A Rahman - 2023 - books.google.com
Studies in Natural Products Chemistry, Volume 79 covers the synthesis, testing and
recording of the medicinal properties of natural products, providing cutting-edge accounts of …

Chemical composition and in vivo/in silico anti-inflammatory activity of an antioxidant, non-toxic essential oil from Thymus algeriensis Boiss. & Reut.

N Righi, A Deghima, D Ismail, PAR Fernandes… - South African Journal of …, 2023 - Elsevier
Abstract Thymus algeriensis Reut & Boiss is an essential oil-bearing plant widely used in
traditional medicine to treat digestive system disorders and numerous inflammatory …

Synthesis, biological evaluation, and molecular modelling of novel quinoxaline-isoxazole hybrid as anti-hyperglycemic

L Phongphane, SNM Radzuan, MHA Bakar… - … Biology and Chemistry, 2023 - Elsevier
In our effort to develop potent anti-hyperglycemic compounds with inhibitory activity against
α-amylase and α-glucosidase, a series of novel quinoxaline-isoxazole moieties were …

Recent developments in the synthesis of N‐heterocyclic compounds as α‐amylase inhibitors via in‐vitro and in‐silico analysis: Future drugs for treating diabetes

P Garg, RS Rawat, H Bhatt, S Kumar… - …, 2022 - Wiley Online Library
In nature, N‐heterocyclic compounds and their derivatives are abundant. They serve as the
building blocks of many biological entities, such as enzymes, alkaloids, hormones …

Recent advances in micro-and nano-bubbles for atherosclerosis applications

A Wijaya, A Maruf, W Wu, G Wang - Biomaterials Science, 2020 - pubs.rsc.org
Atherosclerosis is the most prevalent cause of cardiovascular disease-induced deaths
worldwide. Micro-and nano-bubbles (MNBs) have been developed as the vehicles for …

[HTML][HTML] Fatty acid composition, acute toxicity and anti-inflammatory activity of the n-hexane extract from Ranunculus macrophyllus Desf. roots

A Deghima, N Righi, I Daoud, D Ansorena… - South African Journal of …, 2022 - Elsevier
Ranunculus macrophyllus Desf. is a multipurpose edible medicinal plant, whose roots are
used to treat feminine infertility and to increase weight. The aim of this work was to study for …

Design, synthesis and photoinduced DNA cleavage studies of [1, 2, 4]-triazolo [4, 3-a] quinoxalin-4 (5H)-ones

G Sumran, R Aggarwal, A Mittal, A Aggarwal… - Bioorganic …, 2019 - Elsevier
An expedient and eco-friendly synthesis of 1-aryl/heteroaryl-[1, 2, 4]-triazolo [4, 3-a]
quinoxalin-4 (5H)-ones (4) has been accomplished via iodobenzene diacetate mediated …

Synthesis of 2-styryl-quinazoline and 3-styryl-quinoxaline based sulfonate esters via sp 3 C–H activation and their evaluation for α-glucosidase inhibition

N Satyanarayana, BR Sree, K Sathish… - New Journal of …, 2022 - pubs.rsc.org
Synthesis of 2-styryl-quinazolines and 3-styryl-quinoxaline based sulfonates is reported via
sp3 C–H functionalization in the presence of triethylamine (10 mol%). The resulting …