Matrix metalloproteinases: from molecular mechanisms to physiology, pathophysiology, and pharmacology

LGN de Almeida, H Thode, Y Eslambolchi… - Pharmacological …, 2022 - ASPET
The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

Recent Applications and Future Perspectives of Chemiluminescent and Bioluminescent Imaging Technologies

IM Mostafa, A Abdussalam, YT Zholudov… - … & Biomedical Imaging, 2023 - ACS Publications
Imaging technologies based on chemiluminescence (CL) and bioluminescence (BL) have
seen a tremendous growth in the past decade due to their extensive contributions to …

Rapamycin inhibits corneal inflammatory response and neovascularization in a mouse model of corneal alkali burn

J Li, J Han, Y Shi, M Liu - Experimental eye research, 2023 - Elsevier
Alkali burn-induced corneal injury often causes inflammation and neovascularization and
leads to compromised vision. We previously reported that rapamycin ameliorated corneal …

In situ-forming collagen-hyaluronate semi-interpenetrating network hydrogel enhances corneal defect repair

F Chen, DC Mundy, P Le, YA Seo… - … Vision Science & …, 2022 - tvst.arvojournals.org
Purpose: Millions worldwide suffer vision impairment or blindness from corneal injury, and
there remains an urgent need for a more effective and accessible way to treat corneal …

Effects of plasma-derived exosomes from the normal and thin Bactrian camels on hepatocellular carcinoma and their differences at transcriptome and proteomics …

H Yao, S Yu, Y Luo, M Wang, X Wang, S Xu… - Frontiers in …, 2023 - frontiersin.org
Background Hepatocellular carcinoma (HCC) is a common malignant primary tumor.
Bactrian camels have high economic and social values, but their potential medical value has …

Absence of the Klotho Function Causes Cornea Degeneration with Specific Features Resembling Fuchs Endothelial Corneal Dystrophy and Bullous Keratopathy

CY Wu, DF Song, ZJ Chen, CS Hu, DPC Lin… - Biology, 2024 - mdpi.com
Simple Summary The Klotho null mutation leads to accelerated senescence in many organs.
The effects of an absence of the Klotho function on the cornea remain largely unknown. This …

Effects of plasma-derived exosomes from the normal and thin camels on hepatocellular carcinoma and their differences at transcriptome and proteomics levels

H Yao, S Yu, Y Luo, M Wang, X Wang, Z Bai, Y Zhang… - 2022 - researchsquare.com
Background Hepatocellular carcinoma (HCC) is a common malignant primary tumor.
Camels have high economic and social values, but their potential medical value has not …