Long noncoding RNA HOTAIR polymorphisms and susceptibility to bipolar disorder: a preliminary case–control study

S Sargazi, A Zahedi Abghari, S Mirinejad… - … Nucleotides & Nucleic …, 2022 - Taylor & Francis
Recent studies have shown that long noncoding RNAs contribute to the pathogenesis of
bipolar disorder (BD). In this study, we genotyped four HOX Transcript Antisense Intergenic …

Functional Variants of miR-143 Are Associated with Schizophrenia Susceptibility: A Preliminary Population-Based Study and Bioinformatics Analysis

S Sargazi, F Mirani Sargazi, M Heidari Nia… - Biochemical …, 2022 - Springer
Single nucleotide polymorphisms within genes encoding microRNAs may alter the
expression of microRNAs and their target genes, contributing to the etiology of psychiatric …

[HTML][HTML] Relationship between single nucleotide polymorphisms of GRHL3 and schizophrenia susceptibility: a preliminary case-control study and bioinformatics …

S Sargazi, MH Nia, R Sheervalilou… - … journal of molecular …, 2020 - ncbi.nlm.nih.gov
Grainyhead-like (GRHL) transcription factors were recently linked to the etiology of neural
tube defects (NTDs). Overlapping patterns in the variation of schizophrenia (SCZ) incidence …

HSPB1 gene variants and schizophrenia: A case‐control study in a polish population

M Kowalczyk, K Kucia, A Owczarek… - Disease …, 2022 - Wiley Online Library
Schizophrenia (SCZ) is a severe psychiatric disorder that has a significant genetic
component. HSPB1 (HSP27) is known for its neuroprotective functions under stress …

Relationship between GABRB2 gene polymorphisms and schizophrenia susceptibility: a case-control study and in silico analyses

M Heidari Nia, S Sargazi, R Saravani… - International Journal …, 2022 - Taylor & Francis
Purpose Converging evidence has recently established the significance of γ-aminobutyric
acid neurotransmitter (GABA) system in the development of schizophrenia (SCZ). We aimed …

Investigation of UTR Variants by Computational Approaches Reveal Their Functional Significance in PRKCI Gene Regulation

H Shah, K Khan, Y Badshah, N Mahmood Ashraf… - Genes, 2023 - mdpi.com
Single nucleotide polymorphisms (SNPs) are associated with many diseases including
neurological disorders, heart diseases, diabetes, and different types of cancers. In the …

Multiple recurrent copy number variations (CNVs) in chromosome 22 including 22q11. 2 associated with autism spectrum disorder

S Alhazmi, M Alzahrani, R Farsi, M Alharbi… - Pharmacogenomics …, 2022 - Taylor & Francis
Introduction Autism spectrum disorder (ASD) is a developmental disorder that can cause
substantial social, communication, and behavioral challenges. Genetic factors play a …

Identification of candidate biomarkers and pathways associated with type 1 diabetes mellitus using bioinformatics analysis

M Pujar, B Vastrad, S Kavatagimath, C Vastrad… - Scientific Reports, 2022 - nature.com
Type 1 diabetes mellitus (T1DM) is a metabolic disorder for which the underlying molecular
mechanisms remain largely unclear. This investigation aimed to elucidate essential …

Genetic polymorphism in untranslated regions of PRKCZ influences mRNA structure, stability and binding sites

A Mustafa, M Shabbir, Y Badshah, K Khan, F Abid… - BMC cancer, 2024 - Springer
Background Variations in untranslated regions (UTR) alter regulatory pathways impacting
phenotype, disease onset, and course of disease. Protein kinase C Zeta (PRKCZ), a serine …

Association of Interleukin-6 polymorphisms with schizophrenia and depression: a case-control study

D Lu, M Wang, T Yang, J Wang, B Lin, G Liu… - Laboratory …, 2023 - academic.oup.com
Objective Growing evidence suggests a crossover in genetic susceptibility to schizophrenia
and depression. We aimed to investigate the association of the rs1800795 and rs1800796 …