Nanoparticles (Nps) have revolutionized the landscape of many treatments, by modifying not
only pharmacokinetic properties of the encapsulated agent, but also providing a significant …

Many recent studies focus on the pulmonary delivery of vaccines as it is needle-free, safe,
and effective. Inhaled vaccines enhance systemic and mucosal immunization but still faces …

Despite significant advances in cancer therapy, chemotherapeutic agents are still the main
types of drugs used to treat cancer patients. 5-Fluorouracil (5-FU) is the first-line treatment in …

Delivery of therapeutic peptides via sublingual administration is extremely desired and 3D
printed scaffolds are potential candidates as carriers to enhance insulin delivery. 3D printed …

In present investigation, we developed paclitaxel (PTX)-loaded adenosine (ADN)-
conjugated PLGA nanoparticles for combating triple-negative breast cancer (TNBC), where …

Atorvastatin Calcium (At-Ca) has pleiotropic effect as anti-inflammatory drug beside its main
antihyperlipidemic action. Our study was conducted to modulate the anti-inflammatory effect …

The current study explored the feasibility of a microfluidic preparation of PLGA composite
microspheres with mesoporous silica nanoparticles (MSNs) to finely manipulate the drug …

Purpose The near-infrared fluorescent dye indocyanine green (ICG) has shown great
potential in the photodynamic therapy (PDT) and photothermal therapy (PTT) of cancer …

Central nervous system tuberculosis (CNS-TB) is the most severe form of the disease
especially due to the inability of therapeutics to cross the blood–brain barrier (BBB) …

Background Over the past 30 years, brain tumors have been intensively studied with a
variety of therapeutic approaches. However, brain cancer is still one of the most lethal forms …