Mesoscopic calcium imaging in a head-unrestrained male non-human primate using a lensless microscope
Mesoscopic calcium imaging enables studies of cell-type specific neural activity over large
areas. A growing body of literature suggests that neural activity can be different when …
areas. A growing body of literature suggests that neural activity can be different when …
Large depth-of-field ultra-compact microscope by progressive optimization and deep learning
The optical microscope is customarily an instrument of substantial size and expense but
limited performance. Here we report an integrated microscope that achieves optical …
limited performance. Here we report an integrated microscope that achieves optical …
Pixel-wise programmability enables dynamic high-SNR cameras for high-speed microscopy
High-speed wide-field fluorescence microscopy has the potential to capture biological
processes with exceptional spatiotemporal resolution. However, conventional cameras …
processes with exceptional spatiotemporal resolution. However, conventional cameras …
Long-term optical imaging of the spinal cord in awake behaving mice
Advances in optical imaging and fluorescent biosensors enable study of the spatiotemporal
and long-term neural dynamics in the brain of awake animals. However, methodological …
and long-term neural dynamics in the brain of awake animals. However, methodological …
Multi-region calcium imaging in freely behaving mice with ultra-compact head-mounted fluorescence microscopes
F Xue, F Li, K Zhang, L Ding, Y Wang… - National Science …, 2024 - academic.oup.com
To investigate the circuit-level neural mechanisms of behavior, simultaneous imaging of
neuronal activity in multiple cortical and subcortical regions is highly desired. Miniature head …
neuronal activity in multiple cortical and subcortical regions is highly desired. Miniature head …
Millimeter field-of-view miniature two-photon microscopy for brain imaging in freely moving mice
C Zhao, Y Zhu, D Zhang, Q Fu, M Pan, R Wu… - Optics …, 2023 - opg.optica.org
Development of miniature two-photon microscopy (m2PM) has made it possible to observe
fine structure and activity of neurons in the brain of freely moving animals. However, the …
fine structure and activity of neurons in the brain of freely moving animals. However, the …
[HTML][HTML] Long-term optical imaging of the spinal cord in awake, behaving animals
Advances in optical imaging approaches and fluorescent biosensors have enabled an
understanding of the spatiotemporal and long-term neural dynamics in the brain of awake …
understanding of the spatiotemporal and long-term neural dynamics in the brain of awake …
Computer vision–guided open-source active commutator for neural imaging in freely behaving animals
Significance Recently developed miniaturized neural recording devices that can monitor
and perturb neural activity in freely behaving animals have significantly expanded our …
and perturb neural activity in freely behaving animals have significantly expanded our …
Terabit-scale high-fidelity diamond data storage
In the era of digital information, realizing efficient and durable data storage solutions is
paramount. Innovations in storage capacity, data throughput, device lifespan and energy …
paramount. Innovations in storage capacity, data throughput, device lifespan and energy …
Recent advances in light patterned optogenetic photostimulation in freely moving mice
Optogenetics opened the door to a new era of neuroscience. New optical developments are
under way to enable high-resolution neuronal activity imaging and selective …
under way to enable high-resolution neuronal activity imaging and selective …