In vivo imaging of drug delivery systems in the gastrointestinal tract

W Weitschies, CG Wilson - International journal of pharmaceutics, 2011 - Elsevier
An essential basis for the understanding of the complex interplay between oral drug delivery
systems and gastrointestinal physiology is the ability to relate deposition of the dosage form …

AC biosusceptometry in the study of drug delivery

LA Corá, FG Romeiro, M Stelzer, MF Américo… - Advanced drug delivery …, 2005 - Elsevier
Conventionally, pharmaceutical substances are administered orally because the
gastrointestinal tract possesses the appropriate features for drug absorption. Nevertheless …

Real-time liver uptake and biodistribution of magnetic nanoparticles determined by AC biosusceptometry

CC Quini, AG Próspero, MFF Calabresi… - … , Biology and Medicine, 2017 - Elsevier
We describe the development of a joint in vivo/ex vivo protocol to monitor magnetic
nanoparticles in animal models. Alternating current biosusceptometry (ACB) enables the …

A novel biomagnetic method to study gastric antral contractions

JRA Miranda, RB Oliveira, PL Sousa… - Physics in Medicine …, 1997 - iopscience.iop.org
A novel non-invasive method to study the motion associated with gastric antral contractions
is discussed. The method is based on magnetic flux changes detected by an ac …

Magnetic images of the disintegration process of tablets in the human stomach by ac biosusceptometry

LA Corá, U Andreis, FG Romeiro… - Physics in Medicine …, 2005 - iopscience.iop.org
Oral administration of solid dosage forms is usually preferred in drug therapy. Conventional
imaging methods are essential tools to investigate the in vivo performance of these …

Pharmacomagnetography assessment of the prokinetic effect on metronidazole absorption

GA Soares, GS Rodrigues, LP Buranello… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives This study aimed to evaluate the effects of prucalopride, a prokinetic agent that
acts as a potent serotonin agonist of 5-HT4 receptors, on gastric emptying and small bowel …

Gastrointestinal transit and disintegration of enteric coated magnetic tablets assessed by ac biosusceptometry

LA Cora, FG Romeiro, MF Américo, RB Oliveira… - european journal of …, 2006 - Elsevier
The oral administration is a common route in the drug therapy and the solid pharmaceutical
forms are widely used. Although much about the performance of these formulations can be …

The human vector magnetogastrogram and magnetoenterogram

LA Bradshaw, JK Ladipo, DJ Staton… - IEEE transactions on …, 1999 - ieeexplore.ieee.org
Electrical activity in the gastrointestinal system produces magnetic fields that may be
measured with superconducting quantum interference device magnetometers. Although …

Corona Protein Impacts on Alternating Current Biosusceptometry Signal and Circulation Times of Differently Coated Mnfe2O4 Nanoparticles

AG Prospero, LP Buranello, CAH Fernandes… - …, 2021 - Taylor & Francis
Background: We evaluated the impacts of corona protein (CP) formation on the alternating
current biosusceptometry (ACB) signal intensity and in vivo circulation times of three …

2D quantitative imaging of magnetic nanoparticles by an AC biosusceptometry based scanning approach and inverse problem

GGA Biasotti, AG Próspero, MDT Alvarez, M Liebl… - Sensors, 2021 - mdpi.com
The use of magnetic nanoparticles (MNPs) in biomedical applications requires the
quantitative knowledge of their quantitative distribution within the body. AC …