Primary cilia are solitary, immotile sensory organelles present on most cells in the body that
participate broadly in human health, physiology and disease. Cilia generate a unique …

The primary cilium is a hair-like surface-exposed organelle of the eukaryotic cell that
decodes a variety of signals—such as odorants, light and Hedgehog morphogens—by …

Cilia, organelles that move to execute functions like fertilization and signal to execute
functions like photoreception and embryonic patterning, are composed of a core of nine-fold …

Centrosomes and primary cilia are usually considered as distinct organelles, although both
are assembled with the same evolutionary conserved, microtubule-based templates, the …

Cilia are cellular projections that perform sensory and motile functions in eukaryotic cells. A
defining feature of cilia is that they are evolutionarily ancient, yet not universally conserved …

Centrioles are microtubule-based structures crucial for forming flagella, cilia and
centrosomes. Through these roles, centrioles are critical notably for proper cell motility …

The specific organization of the neuronal microtubule cytoskeleton in axons and dendrites is
an evolutionarily conserved determinant of neuronal polarity that allows for selective cargo …

Cilia both receive and send information, the latter in the form of extracellular vesicles (EVs).
EVs are nano-communication devices that influence cell, tissue, and organism behavior …

Proximity-dependent labeling approaches such as BioID have been a great boon to studies
of protein-protein interactions in the context of cytoskeletal structures such as centrosomes …

During mitosis in animal cells, the centrosome acts as a microtubule organizing center
(MTOC) to assemble the mitotic spindle. MTOC function at the centrosome is driven by …