Signaling pathways in rheumatoid arthritis: implications for targeted therapy

Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

A structured literature review of the burden of illness and unmet needs in patients with rheumatoid arthritis: a current perspective

PC Taylor, A Moore, R Vasilescu, J Alvir… - Rheumatology …, 2016 - Springer
While rheumatologists often focus on treatment targets, for many patients with rheumatoid
arthritis (RA), control over pain and fatigue, as well as sustaining physical function and …

Prevalence of rheumatoid arthritis in the United States adult population in healthcare claims databases, 2004–2014

TM Hunter, NN Boytsov, X Zhang, K Schroeder… - Rheumatology …, 2017 - Springer
This study aimed to determine the prevalence of rheumatoid arthritis in the United States
(US) adult insured population from 2004 to 2014. This was an observational, retrospective …

The need to address the burden of musculoskeletal conditions

AD Woolf, J Erwin, L March - Best practice & research Clinical …, 2012 - Elsevier
Musculoskeletal conditions are common in men and women of all ages across all socio-
demographic strata of society. They are the most common cause of severe long-term pain …

Prevalence of arthritis according to age, sex and socioeconomic status in six low and middle income countries: analysis of data from the World Health Organization …

SL Brennan-Olsen, S Cook, MT Leech, SJ Bowe… - BMC musculoskeletal …, 2017 - Springer
Background In higher income countries, social disadvantage is associated with higher
arthritis prevalence; however, less is known about arthritis prevalence or determinants in low …

The burden of disease in rheumatoid arthritis

T Uhlig, RH Moe, TK Kvien - Pharmacoeconomics, 2014 - Springer
Rheumatoid arthritis (RA) is a chronic inflammatory disease which, if left untreated, leads to
functional disability, pain, reduced health-related quality of life and premature mortality …

Burden of disease in treated rheumatoid arthritis patients: going beyond the joint

M Cutolo, GD Kitas, PLCM van Riel - Seminars in arthritis and rheumatism, 2014 - Elsevier
Objective The disease burden in rheumatoid arthritis (RA) extends beyond the joint. This
article evaluates the physical and psychosocial extra-articular burden of treated RA and …

Association between malnutrition and quality of life in elderly patients with rheumatoid arthritis

W Tański, J Wójciga, B Jankowska-Polańska - Nutrients, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a progressive articular disease. In addition to damaging the
joints, it may cause multiple organ complications, and considerably impair the patient's …

The effect of physical exercise on rheumatoid arthritis: an overview of systematic reviews and meta‐analysis

H Hu, A Xu, C Gao, Z Wang… - Journal of advanced …, 2021 - Wiley Online Library
Aims To determine which outcomes will be improved by different exercise interventions and
the evidence quality for each intervention. Design Overview of systematic reviews and meta …

Suppressing inflammation in rheumatoid arthritis: does patient global assessment blur the target? A practice‐based call for a paradigm change

RJO Ferreira, C Duarte, M Ndosi, M de Wit… - Arthritis care & …, 2018 - Wiley Online Library
Objective In current management paradigms of rheumatoid arthritis (RA), patient global
assessment (PGA) is crucial to decide whether a patient has attained remission (target) or …