Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has rapidly progressed
from a research tool to a clinical application for the diagnosis and management of …
from a research tool to a clinical application for the diagnosis and management of …
[HTML][HTML] Glutaredoxin: Discovery, redox defense and much more
Glutaredoxin, Grx, is a small protein containing an active site cysteine pair and was
discovered in 1976 by Arne Holmgren. The Grx system, comprised of Grx, glutathione …
discovered in 1976 by Arne Holmgren. The Grx system, comprised of Grx, glutathione …
Mirusviruses link herpesviruses to giant viruses
DNA viruses have a major influence on the ecology and evolution of cellular organisms,,–,
but their overall diversity and evolutionary trajectories remain elusive. Here we carried out a …
but their overall diversity and evolutionary trajectories remain elusive. Here we carried out a …
A sister lineage of the Mycobacterium tuberculosis complex discovered in the African Great Lakes region
JCS Ngabonziza, C Loiseau, M Marceau… - Nature …, 2020 - nature.com
The human-and animal-adapted lineages of the Mycobacterium tuberculosis complex
(MTBC) are thought to have expanded from a common progenitor in Africa. However, the …
(MTBC) are thought to have expanded from a common progenitor in Africa. However, the …
Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history
Human tuberculosis (TB) is caused by members of the Mycobacterium tuberculosis complex
(MTBC). The MTBC comprises several human-adapted lineages known as M. tuberculosis …
(MTBC). The MTBC comprises several human-adapted lineages known as M. tuberculosis …
[HTML][HTML] EukProt: a database of genome-scale predicted proteins across the diversity of eukaryotes
DJ Richter, C Berney, JFH Strassert… - Peer Community …, 2022 - peercommunityjournal.org
EukProt is a database of published and publicly available predicted protein sets selected to
represent the breadth of eukaryotic diversity, currently including 993 species from all major …
represent the breadth of eukaryotic diversity, currently including 993 species from all major …
A New Phylogenetic Framework for the Animal-Adapted Mycobacterium tuberculosis Complex
Tuberculosis (TB) affects humans and other animals and is caused by bacteria from the
Mycobacterium tuberculosis complex (MTBC). Previous studies have shown that there are at …
Mycobacterium tuberculosis complex (MTBC). Previous studies have shown that there are at …
Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut
L Laganenka, JW Lee, L Malfertheiner… - Nature …, 2023 - nature.com
Bacteria communicate and coordinate their behaviour at the intra-and interspecies levels by
producing and sensing diverse extracellular small molecules called autoinducers …
producing and sensing diverse extracellular small molecules called autoinducers …
Direct RNA sequencing and early evolution of SARS-CoV-2
Fundamental aspects of SARS-CoV-2 biology remain to be described, having the potential
to provide insight to the response effort for this high-priority pathogen. Here we describe the …
to provide insight to the response effort for this high-priority pathogen. Here we describe the …
Reply to:“Re-evaluating the evidence for a universal genetic boundary among microbial species”
It has recently been reported 1 that when one removes multiple genomes within a named
species or species defined at the 95% genome-aggregate average nucleotide identity (ANI) …
species or species defined at the 95% genome-aggregate average nucleotide identity (ANI) …