The blood-brain barrier (BBB) is vital for maintaining brain homeostasis by enabling an
exquisite control of exchange of compounds between the blood and the brain parenchyma …

The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

Forming the inner layer of the vascular system, endothelial cells (ECs) facilitate a multitude
of crucial physiological processes throughout the body. Vascular ECs enable the vessel wall …

BACKGROUND Each organ in the human body has its own capillary bed to carry out its
distinctive and versatile functions in response to dynamically changing systemic and local …

Abstract Purpose of Review For many years, exercise was controversial in multiple sclerosis
(MS) and thought to exacerbate symptoms and fatigue. However, having been found to be …

Most risk variants for brain disorders identified by genome-wide association studies reside in
the noncoding genome, which makes deciphering biological mechanisms difficult. A …

Minimally invasive detection of cell death could prove an invaluable resource in many
physiologic and pathologic situations. Cell-free circulating DNA (cfDNA) released from dying …

Scientists and health professionals are exhaustively trying to contain the coronavirus
disease 2019 (COVID-19) pandemic by elucidating viral invasion mechanisms, possible …

The disruption of blood–brain barrier (BBB) for multiple sclerosis (MS) pathogenesis has a
double effect: early on during the onset of the immune attack and later for the CNS self …

'Leaky gut'syndrome, long-associated with celiac disease, has attracted much attention in
recent years and for decades, was widely known in complementary/alternative medicine …